PFI-6 is a selective and non-cytotoxic probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3), with IC50 values of 140 nM for MLLT1 and 160 nM for MLLT3. It serves as a molecular tool to investigate the role of MLLT1/3 in diseases and genome validation studies [1].
PFI-6 is a selective and non-cytotoxic probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3), with IC50 values of 140 nM for MLLT1 and 160 nM for MLLT3. It serves as a molecular tool to investigate the role of MLLT1/3 in diseases and genome validation studies [1].
PFI-6 is a selective and non-cytotoxic probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3), with IC50 values of 140 nM for MLLT1 and 160 nM for MLLT3. It serves as a molecular tool to investigate the role of MLLT1/3 in diseases and genome validation studies [1].
化学信息
分子量
391.42
分子式
C22H21N3O4
CAS No.
2675452-91-0
储存&溶解度
存储
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