MLS-0437605

Name: MLS-0437605
Brand: TargetMol
SKU: T40968
Rating: 4.5 (1 reviews)

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产品编号 T40968Cas号 862975-18-6

MLS-0437605 is a potent and selective inhibitor of dual-specificity phosphatase 3 (DUSP3), with an IC50 of 3.7 μM. It exhibits higher selectivity towards DUSP3 in comparison to DUSP22 and other protein tyrosine phosphatases (PTPs).

MLS-0437605

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产品编号 T40968Cas号 862975-18-6

规格	价格	库存	数量
2 mg	¥ 4,380	5日内发货
5 mg	¥ 7,000	5日内发货

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产品描述	MLS-0437605 is a potent and selective inhibitor of dual-specificity phosphatase 3 (DUSP3), with an IC50 of 3.7 μM. It exhibits higher selectivity towards DUSP3 in comparison to DUSP22 and other protein tyrosine phosphatases (PTPs).
体外活性	MLS-0437605 efficiently inhibits platelet aggregation in response to collagen related peptide (CRP) and rhodocytin, but not after stimulation with thromboxane. MLS-0437605 causes a decrease in pY of a ~70-kDa band after stimulation with CRP or rhodocytin. Tyrosine phosphorylation of immunoprecipitated Syk and PLCγ2 is also reduced by MLS-0437605[1].