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VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively).
VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 295 | 5日内发货 | |
5 mg | ¥ 497 | 5日内发货 | |
10 mg | ¥ 747 | 5日内发货 | |
1 mL x 10 mM (in DMSO) | ¥ 983 | 5日内发货 |
产品描述 | VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively). |
靶点活性 | mGlu5:17.9 μM (EC50), mGlu4 (rat):290 nM (EC50), mGlu6:6.8 μM (EC50), mGlu4 (human):1.1 μM (EC50) |
分子量 | 269.13 |
分子式 | C12H10Cl2N2O |
CAS No. | 1414842-70-8 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 100 mg/mL (371.57 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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