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BMS 961
还可以产品编号 T22611Cas号 185629-22-5
BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist (IC50: 30 nM).
BMS 961
还可以产品编号 T22611Cas号 185629-22-5
BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist (IC50: 30 nM).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 857 | 35日内发货 | |
| 10 mg | ¥ 3,970 | 35日内发货 |
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产品介绍
生物活性
化学信息
| 产品描述 | BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist (IC50: 30 nM). |
| 体外活性 | In vitro, the application of BMS961on mouse ear skin was found to cause a significant increase of thymic stromal lymphopoietin (TSLP) transcripts1. In addition, exposure of BMS861 on limbs at low concentration leads to retarded growth of the zeugopod (long bones) and intactness of autopod (paw). However, a high concentration of BMS961treatment caused equal undifferentiation of both limb regions 2. |
| 体内活性 | In WT mice, RARγ agonists BMS961treatment resulted in an increase of the ear TSLP transcripts and serum TSLP, which indicates an involvement of RAR-mediated events in transcriptional activation of TSLP expression1. |
| 分子量 | 399.46 |
| 分子式 | C23H26FNO4 |
| CAS No. | 185629-22-5 |
| 密度 | 1.241 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | DMSO: <39.95 mg/mL |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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