EN460

Name: EN460
Brand: TargetMol
SKU: T15218
Price: 259 USD
Availability: InStock
Rating: 4.5 (1 reviews)

产品编号 T15218Cas号 496807-64-8

EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation.

EN460

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产品编号 T15218Cas号 496807-64-8

EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation.

规格	价格	库存
2 mg	¥ 594	5日内发货
5 mg	¥ 1,140	5日内发货
50 mg	¥ 5,150	6-8周
100 mg	¥ 7,940	6-8周

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产品介绍

生物活性

产品描述	EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation.
体外活性	Exposure of cells to EN460 or QM295 resulted in the accumulation of an ERO1α form with lower mobility, indicative of the reduced state. EN460 and QM295 activate an unfolded protein response reporter in cultured 293T cells.

化学信息

分子量	460.79
分子式	C₂₂H₁₂ClF₃N₂O₄
CAS No.	496807-64-8

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 12.5 mg/mL (27.13 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1702 mL	10.8509 mL	21.7019 mL	108.5093 mL
5 mM	0.4340 mL	2.1702 mL	4.3404 mL	21.7019 mL
10 mM	0.2170 mL	1.0851 mL	2.1702 mL	10.8509 mL
20 mM	0.1085 mL	0.5425 mL	1.0851 mL	5.4255 mL