Isoetharine (hydrochloride) (compound I) is a selective, short-acting and orally active β-adrenergic receptor agonist widely used as a bronchodilator in inhalation therapy studies[1].

Isoetharine (hydrochloride) (I) (oral; 0, 800, 1400, 2000 and 2500 mg/kg/day; 2 weeks) is high variable of plasma levels in dose-ranging studies at 1 h after oral medication [1]. Animal Model: Sprague-Dawley rats [1] Dosage: 0, 800, 1400, 2000 and 2500 mg/kg Administration: oral; 0, 800, 1400, 2000 and 2500 mg/kg/day; 2 weeks Result: Observed highly variable of plasma levels in dose-ranging studies at 1 h after oral medication.