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PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.
PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥ 3,780 | 35日内发货 |
产品描述 | PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity. |
靶点活性 | EZH2 (Y641N):3.0 nM (ki), EZH2 (WT):0.7 nM (ki) |
体外活性 | PF-06726304 inhibits the proliferation of Karpas-422 cells that harbor wild-type EZH2 (IC50 of 25 nM)[1]. |
体内活性 | In a subcutaneous Karpas-422 xenograft model,PF-06726304 inhibits tumor growth and induces robust modulation of downstream biomarkers [1]. |
分子量 | 506.38 |
分子式 | C24H25Cl2N3O5 |
CAS No. | 2080306-28-9 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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