ATWLPPR Peptide TFA

Name: ATWLPPR Peptide TFA
Brand: TargetMol
SKU: T10408
Rating: 4.5 (1 reviews)

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产品编号 T10408

ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor and inhibits VEGF165 binding to NRP-1. It has the potential in reducing the early retinal damage caused by diabetes.

ATWLPPR Peptide TFA

还可以

产品编号 T10408

ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor and inhibits VEGF165 binding to NRP-1. It has the potential in reducing the early retinal damage caused by diabetes.

规格	价格	库存	数量
50 mg	询价	期货
100 mg	询价	期货

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产品介绍

生物活性

产品描述	ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor and inhibits VEGF165 binding to NRP-1. It has the potential in reducing the early retinal damage caused by diabetes.
体外活性	ATWLPPR Peptide TFA inhibits VEGF165 binding to NRP-1 by 82% at 100 μM [1].
体内活性	ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes. ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF, and ICAM-1) in the retina [2].

化学信息

分子量	954
分子式	C₄₂H₆₂F₃N₁₁O₁₁
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

H2O: 50 mg/mL (52.41 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	1.0482 mL	5.2411 mL	10.4822 mL	52.4109 mL
5 mM	0.2096 mL	1.0482 mL	2.0964 mL	10.4822 mL
10 mM	0.1048 mL	0.5241 mL	1.0482 mL	5.2411 mL
20 mM	0.0524 mL	0.2621 mL	0.5241 mL	2.6205 mL
50 mM	0.0210 mL	0.1048 mL	0.2096 mL	1.0482 mL