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AGH-107为一种5-HT7受体激动剂,具有高选择性且能透过血脑屏障,其Ki值达到6 nM,而EC50值为19 nM。在HEK-293及HepG2细胞培养中,AGH-107展现了针对中枢神经系统相关靶标的高选择性、良好的代谢稳定性以及低毒性特点。
AGH-107为一种5-HT7受体激动剂,具有高选择性且能透过血脑屏障,其Ki值达到6 nM,而EC50值为19 nM。在HEK-293及HepG2细胞培养中,AGH-107展现了针对中枢神经系统相关靶标的高选择性、良好的代谢稳定性以及低毒性特点。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures. |
分子量 | 337.16 |
分子式 | C13H12IN3 |
CAS No. | 2172907-10-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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