PAT-1251 Hydrochloride

Name: PAT-1251 Hydrochloride
Brand: TargetMol
SKU: T12371
Price: 828 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T12371Cas号 2098884-53-6

PAT-1251 Hydrochloride is a potent, selective and oral inhibitor of lysyl oxidase-like 2 (LOXL2)(hLOXL2 and hLOXL3 with IC50s of 0.71 and 1.17 μM , respectively),

PAT-1251 Hydrochloride

还可以

产品编号 T12371Cas号 2098884-53-6

PAT-1251 Hydrochloride is a potent, selective and oral inhibitor of lysyl oxidase-like 2 (LOXL2)(hLOXL2 and hLOXL3 with IC50s of 0.71 and 1.17 μM , respectively),

规格	价格	库存
25 mg	¥ 10,600	1-2周
50 mg	¥ 13,800	1-2周
100 mg	¥ 17,500	1-2周

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产品介绍

生物活性

产品描述	PAT-1251 Hydrochloride is a potent, selective and oral inhibitor of lysyl oxidase-like 2 (LOXL2)(hLOXL2 and hLOXL3 with IC50s of 0.71 and 1.17 μM , respectively),
靶点活性	LOXL2 (human):0.71 μM , LOXL3 (human):1.17 μM , LOXL2 (dog):0.16 μM , LOXL2 (mouse):0.10 μM , LOXL2 (rat):0.12 μM
体外活性	PAT-1251 shows highly selective for LOXL2 over other key members of the amine oxidase family, such as the copper-dependent amine oxidases semicarbazide-sensitive amine oxidase (SSAO) and diamine oxidase (DAO), in addition to the flavin-dependent monoamine oxidases A (MAO-A) and B (MAO-B), with <10% inhibition at 10 μM[1].