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MMG-11
产品编号 T16123Cas号 313254-94-3
MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity.
MMG-11
产品编号 T16123Cas号 313254-94-3
MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 465 | 5日内发货 | |
| 5 mg | ¥ 894 | 5日内发货 | |
| 100 mg | ¥ 7,890 | 6-8周 |
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产品介绍
生物活性
化学信息
| 产品描述 | MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity. |
| 体外活性 | MMG-11 (0.01-100?μM) shows no cytotoxic effects up to 100?μM in peripheral blood mononuclear cells (PBMCs). MMG-11 neither displays cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β, or TNF . |
| 分子量 | 306.27 |
| 分子式 | C15H14O7 |
| CAS No. | 313254-94-3 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
计算器
体内实验配液计算器
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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