BI-9321

Name: BI-9321
Brand: TargetMol
SKU: T10538
Price: 247 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T10538Cas号 2387510-86-1

BI-9321 is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.

BI-9321

还可以

产品编号 T10538Cas号 2387510-86-1

BI-9321 is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.

规格	价格	库存
25 mg	¥ 13,800	6-8周
50 mg	¥ 18,000	6-8周
100 mg	¥ 28,800	6-8周

大包装 & 定制

加入购物车

实验操作小课堂

联系我们获取更多批次信息

资源下载

产品操作手册

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	BI-9321 is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.
靶点活性	NSD3-PWWP1:(kd)166 nM
体外活性	BI-9321 specifically disrupts histone interactions of the NSD3-PWWP1 domain (IC50: 1.2 μM in U2OS cells). BI-9321 is targeting the methyl-lysine binding site of the PWWP1 domain and cellular target engagement at 1?μM. BI-9321 downregulates Myc messenger RNA expression and reduces proliferation in MOLM-13 cells.