DLK-IN-1

Name: DLK-IN-1
Brand: TargetMol
SKU: T11056
Price: 397 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T11056Cas号 1620574-24-4

DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration exceeds the concentration required for DLK inhibition in the brain, so it has good tolerance Acceptability.

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DLK-IN-1

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产品编号 T11056Cas号 1620574-24-4

规格	价格	库存
2 mg	¥ 3,630	5日内发货
5 mg	¥ 4,570	5日内发货
25 mg	¥ 17,600	10-14周
50 mg	¥ 22,900	10-14周
100 mg	¥ 31,500	10-14周
1 mL x 10 mM (in DMSO)	¥ 4,930	5日内发货

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration exceeds the concentration required for DLK inhibition in the brain, so it has good tolerance Acceptability.
靶点活性	DLK:ki:3 nM

化学信息

分子量	423.43
分子式	C₂₀H₂₄F₃N₅O₂
CAS No.	1620574-24-4
密度	1.59 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 62.5 mg/mL (147.60 mM), Sonication is recommended.

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	2.3617 mL	11.8083 mL	23.6167 mL	118.0833 mL
5 mM	0.4723 mL	2.3617 mL	4.7233 mL	23.6167 mL
10 mM	0.2362 mL	1.1808 mL	2.3617 mL	11.8083 mL
20 mM	0.1181 mL	0.5904 mL	1.1808 mL	5.9042 mL
50 mM	0.0472 mL	0.2362 mL	0.4723 mL	2.3617 mL
100 mM	0.0236 mL	0.1181 mL	0.2362 mL	1.1808 mL