Chitin synthase inhibitor 1

Name: Chitin synthase inhibitor 1
Brand: TargetMol
SKU: T62068
Price: 164 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T62068

Chitin synthase inhibitor 1 是有效的、选择性的几丁质合酶 (CHS) 抑制剂，IC50值为0.12 mM。Chitin synthase inhibitor 1 强效抑制耐药真菌变体。

Chitin synthase inhibitor 1

还可以

产品编号 T62068

Chitin synthase inhibitor 1 是有效的、选择性的几丁质合酶 (CHS) 抑制剂，IC50值为0.12 mM。Chitin synthase inhibitor 1 强效抑制耐药真菌变体。

规格	价格	库存
25 mg	¥ 10,600	10-14周
50 mg	¥ 13,800	10-14周
100 mg	¥ 17,500	10-14周

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产品介绍

生物活性

产品描述

Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with IC50 of 0.12 mM. Chitin synthase inhibitor 1 potently inhibits drug-resistant fungi variants.

体外活性

Chitin synthase inhibitor 1 (compound 5a) shows broad-spectrum antifungal activity (MIC=4 μg/mL in Candidaalbicans (C. albicans) ATCC 76615 and Aspergillus fumigatus (A. fumigatus) GIMCC 3.19; MIC=8 μg/mL in Aspergillus flavus (A. flavus) ATCC 16870 and Crytococcusneoformans (C. neoformans) ATCC 32719) [1]. Chitin synthase inhibitor 1 shows antifungal activity against drug-resistant fungi variants (MIC=32 μg/mL in Fluconazoleresistant C.albicans ATCC 76615R, Fluconazole-resistant A.fumigatus GIMCC 3.19R, and Fluconazole-resistant C. neoformans ATCC 32719R, Micafunginresistant C.albicans ATCC 76615R’; MIC=16 μg/mL in Fluconazole-resistant A.flavus ATCC 16870R) [1].