D-Cl-amidine

Name: D-Cl-amidine
Brand: TargetMol
SKU: T10932
Price: 592 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T10932Cas号 1404060-15-6

D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.

还可以

产品编号 T10932Cas号 1404060-15-6

D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.

大包装 & 定制

加入购物车

该分子属于定制产品。TargetMol拥有优秀的合成团队，经验和能力，可以为您提供高性价比的产品。但由于客观因素，研发中会存在小概率合成不成功的情况，还请理解，如您有任何问题，欢迎咨询，我们将竭诚为您服务。

实验操作小课堂

联系我们获取更多批次信息

资源下载

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.
体外活性	D-D-Cl-amidine (200-400μM) can effectively reduce the cell viability of MDA-MB-231 cells . D-Cl-amidine increased the activity of caspase 3, indicating that inhibition of PAD1 resulted in increased apoptosis.
体内活性	D-Cl-amidine administered intravenously at a dose of 2.5 mg / kg was still detected at a concentration of approximately 21 nM in serum after 2 h and 4 h at a concentration of approximately 10 nM. Intraperitoneal injection of D-Cl-amidine at a dose of 10 mg / kg was still observed at a concentration of approximately 10 nM at 4 h.