购物车
- 全部删除
- 您的购物车当前为空
AD1058 是一种高效、选择性且能够透过血脑屏障的 ATR 抑制剂 (IC50 = 1.6 nM),具有显著的体内抗癌活性,通过抑制细胞增殖、破坏细胞周期和诱导细胞凋亡,常用于脑转移和中枢神经系统转移的研究中。
AD1058 是一种高效、选择性且能够透过血脑屏障的 ATR 抑制剂 (IC50 = 1.6 nM),具有显著的体内抗癌活性,通过抑制细胞增殖、破坏细胞周期和诱导细胞凋亡,常用于脑转移和中枢神经系统转移的研究中。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 现货 | |
50 mg | ¥ 13,800 | 现货 | |
100 mg | ¥ 17,500 | 现货 |
产品描述 | AD1058 is a potent and selective ATR inhibitor (IC50 = 1.6 nM) that crosses the blood-brain barrier with significant in vivo anticancer activity. It is commonly used in the study of brain metastasis and CNS metastasis by inhibiting cell proliferation, disrupting the cell cycle and inducing apoptosis. |
靶点活性 | LCK:2594.00 nM, ATR:1.6 nM, mTOR:45.83 nM, ARK5:7314.00 nM |
别名 | AD 1058 |
分子量 | 412.47 |
分子式 | C19H20N6O3S |
CAS No. | 2907782-78-7 |
Smiles | C[C@H]1N(C2=C3C(=NC(=N2)C4=C5C(=NC=C4)NC=C5)N(S(C)(=O)=O)C=C3)CCOC1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 80 mg/mL (193.95 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
|
评论内容