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HQL-79
还可以产品编号 T15503Cas号 162641-16-9
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
HQL-79
还可以产品编号 T15503Cas号 162641-16-9
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 945 | 5日内发货 | |
| 5 mg | ¥ 1,580 | 5日内发货 | |
| 10 mg | ¥ 2,610 | 5日内发货 |
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生物活性
化学信息
| 产品描述 | HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS. |
| 靶点活性 | HPGDS:(kd)0.8 μM, HPGDS:6 μM |
| 体外活性 | HQL-79 is a competitive inhibitor against substrate PGH2. HQL-79 is also a non-competitive one against GSH[1]. |
| 分子量 | 377.48 |
| 分子式 | C22H27N5O |
| CAS No. | 162641-16-9 |
| 密度 | 1.21g/cm3 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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