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Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor.
Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | Emiglitate is a selective and competitive α-glucoside hydrolase inhibitor. |
体外活性 | Emiglitate inhibits the glucose-stimulated insulin release in parallel. It also has an inhibitory effect on the activities of acid glucan-1,4-α-glucosidase and acid α-glucosidase. The CO-induced amplification of the glucose-stimulated insulin release as well as of the increased activities of the acid α-glucoside hydrolases are abrogated by emiglitate. Which showed the same levels as in the absence of CO. The CO-induced rise in the activities of acid phosphatase and acid N-acetyl-β-D-glucosaminidase is not appreciably affected by emiglitate. The activities of acid phosphatase and N-acetyl-β-D-glucosaminidase tend to increase in the presence of the α-glucoside hydrolase inhibitor [1]. |
体内活性 | Emiglitate in the amount of 5 mg/kg b.wt. does not induce significant changes either of glycogen concentrations or at the EM-level. Emiglitate causes a significant, dose-dependent increase of hepatic glycogen concentrations, in fasted rats. The increase in hepatic glycogen is due to lysosomal storage of glycogen only [2]. |
别名 | BAY o 1248 |
分子量 | 355.38 |
分子式 | C17H25NO7 |
CAS No. | 80879-63-6 |
密度 | 1.31g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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