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VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an impressive IC 50 value of 0.34 nM. This compound exhibits notable antitumor activity, capable of inducing apoptosis and cell cycle arrest specifically at the G1 phase [1].
VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an impressive IC 50 value of 0.34 nM. This compound exhibits notable antitumor activity, capable of inducing apoptosis and cell cycle arrest specifically at the G1 phase [1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an impressive IC 50 value of 0.34 nM. This compound exhibits notable antitumor activity, capable of inducing apoptosis and cell cycle arrest specifically at the G1 phase [1]. |
体外活性 | VEGFR-2-IN-23 (compound 11b) shows antitumor activity with IC 50 s of 23, 0.8, 1.3, 46 nM for PC3, DU145, MCF-7, MDA-MB435 cells, respectively [1]. |
体内活性 | VEGFR-2-IN-23 (5, 10 mg/kg; i.p.) shows inhibits the tumor growth in MCF-7 xenograft tumor models [1]. |
分子量 | 381.39 |
分子式 | C22H15N5O2 |
CAS No. | 2411174-53-1 |
存储 | Shipping with blue ice. |
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