3-deazauridine

3-Deazauridine (NSC-126849) 是一种尿苷的结构类似物，通过竞争性抑制胞苷三磷酸合成酶来抑制胞苷-5'-三磷酸的生物合成，这种合成酶被认为是这种核苷类似物的主要作用方式。

3'-beta-C-Methyl-3-deazauridine is a Nucleoside Derivative - 3'-Modified nucleoside, 3-Deazauridine.

3'-beta-C-Ethynyl-3-deazauridine is a Nucleoside Derivative - 3'-Modified nucleoside, 3-Deazauridine.

Nucleosides and Reagents - Fluoro-modified nucleoside; 3-Deazauridine; Pyridine nucleoside

Nucleoside Derivatives - 5’-Modified nucleosides; 3-Deazauridines

Nucleoside Derivatives –Azido-nucleosides, 3-Deaza uridines, 3’-Modified nucleosides; Pyridine nucleosides

Nucleoside Derivatives - 3’-Deoxy nucleosides, 3-Deazauridines, Pyridine nucleosides

Nucleosides and Reagents - 3-Dezauridine; Pyridine nucleoside

2’-β-C-Methyl-3-deazauridine 是嘌呤核苷类似物，广泛应用于靶向惰性淋巴系统恶性肿瘤的抗肿瘤活性中。其主要通过抑制 DNA 合成及诱导细胞凋亡(apoptosis)等机制发挥抗癌作用。