hCAI/II-IN-3

Name: hCAI/II-IN-3
Brand: TargetMol
SKU: T61832
Price: 117 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T61832Cas号 2480283-93-8

hCAI/II-IN-3 (compound 5b) is a highly effective dual inhibitor of hCA I/II enzymes. It exhibits Ki values of 51.25, 13.15, and 42.18 nM for hCA I, hCA II, and hCA Ⅸ, respectively. hCAI/II-IN-3 demonstrates anti-hypoxic properties against acute mountain sickness (AMS) and exhibits low cellular activity [1].

hCAI/II-IN-3

还可以

产品编号 T61832Cas号 2480283-93-8

规格	价格	库存
25 mg	¥ 10,600	6-8周
50 mg	¥ 13,800	6-8周
100 mg	¥ 17,500	6-8周

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生物活性

产品描述	hCAI/II-IN-3 (compound 5b) is a highly effective dual inhibitor of hCA I/II enzymes. It exhibits Ki values of 51.25, 13.15, and 42.18 nM for hCA I, hCA II, and hCA Ⅸ, respectively. hCAI/II-IN-3 demonstrates anti-hypoxic properties against acute mountain sickness (AMS) and exhibits low cellular activity [1].
体外活性	hCAI/II-IN-3 (compound 5b) (5-200 μM, 48 hours; HEK293T cells) has no obvious toxicity at HEK293T cells [1]. Cell Cytotoxicity Assay [1] Cell Line: Embryonic kidney (HEK293T) cells Concentration: 5, 25, 50, 100 and 200 μM Incubation Time: 48 hours Result: Had no apparent cytotoxicity.