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Thalidomide-Piperazine-PEG3-NH2
产品编号 T39895Cas号 2357113-68-7
别名 Thalidomide-Piperazine-PEG3-NH2
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter.
Thalidomide-Piperazine-PEG3-NH2
产品编号 T39895 别名 Thalidomide-Piperazine-PEG3-NH2Cas号 2357113-68-7
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 6,267 | 期货 | |
| 50 mg | ¥ 9,867 | 期货 |
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产品介绍
生物活性
化学信息
| 产品描述 | Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter. |
| 体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| 别名 | Thalidomide-Piperazine-PEG3-NH2 |
| 分子量 | 517.583 |
| 分子式 | C25H35N5O7 |
| CAS No. | 2357113-68-7 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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