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1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 主要用作构建脂质体的脂质类化合物,是制备以同心磷脂双层膜囊泡为基础的药物递送系统的关键成分。该系统在抗癌和抗感染治疗中具有重要应用,能有效载运高极性的水溶性药物到脂质体的内部水相空间,同时也允许亲脂性药物整合进脂质双层。此外,1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 在递送反义寡核苷酸方面显示出优势,解决了低效的细胞摄取和快速体内流失的问题。
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 主要用作构建脂质体的脂质类化合物,是制备以同心磷脂双层膜囊泡为基础的药物递送系统的关键成分。该系统在抗癌和抗感染治疗中具有重要应用,能有效载运高极性的水溶性药物到脂质体的内部水相空间,同时也允许亲脂性药物整合进脂质双层。此外,1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 在递送反义寡核苷酸方面显示出优势,解决了低效的细胞摄取和快速体内流失的问题。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium is a lipid compound utilized in the formulation of liposomes. Liposomes, composed of concentric phospholipid bilayer vesicles, serve as integral components in drug delivery systems aimed at oncology and anti-infection treatments. They efficiently encapsulate hydrophilic (highly polar) solutes within their aqueous interior, while lipophilic solutes are integrated into and become part of the lipid bilayer. This compound is particularly effective in delivering antisense oligonucleotides, addressing challenges such as poor cellular uptake and rapid degradation in the body. |
分子量 | 805.99 |
分子式 | C42H73NNaO10P |
CAS No. | 321883-39-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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