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Anti-EFNB1 Monoclonal Antibody-Biotin is a Biotin-conjugated rabbit antibody targeting EFNB1. Anti-EFNB1 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
Anti-EFNB1 Monoclonal Antibody-Biotin is a Biotin-conjugated rabbit antibody targeting EFNB1. Anti-EFNB1 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 1,321.82¥ 2,279 | 7日内发货 | |
50 μg | ¥ 2,202.84¥ 3,798 | 7日内发货 | |
100 μg | ¥ 3,304.26¥ 5,697 | 7日内发货 |
产品描述 | Anti-EFNB1 Monoclonal Antibody-Biotin is a Biotin-conjugated rabbit antibody targeting EFNB1. Anti-EFNB1 Monoclonal Antibody-Biotin can be used in ELISA, FACS. |
别名 | EPH-related receptor tyrosine kinase ligand 2, EFL-3, ELK ligand, Ephrin-B1 |
Ig Type | Rabbit monoclonal IgG |
交叉反应 | Human |
验证活性 | Flow cytometry analysis of EFNB1 overexpressed 327F cells with TMAZ-0223B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
应用 | ELISA, FACS |
推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Single-pass type I membrane |
构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNB1 protein. |
纯化方式 | Protein A Affinity Purified |
性状 | Liquid |
缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
纯度 | > 95% as determined by SDS-PAGE. |
研究背景 | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed: 7973638, PubMed: 8070404). Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells (PubMed: 7973638, PubMed: 8070404). Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed: 7973638, PubMed: 8070404). Can also bind EPHB2 and EPHB3 (PubMed: 8070404). Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity). May play a role in constraining the orientation of longitudinally projecting axons (By similarity) |
偶联 | Biotin |
其他可选修饰符 | APC/PE/AF488/AF555/AF647 |
可提供抗体种类 | 1 |
免疫原 | EFNB1 |
抗原种属 | Human |
基因ID | 1947 |
Uniprot ID | |
研究领域 | Cytokines |
分子量 | 150 kDa |
储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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