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Anti-MUC1 Monoclonal Antibody
产品编号 TMAZ-0113
别名 PEMT, Carcinoma-associated mucin, Tumor-associated mucin, Episialin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3, Mucin-1, H23AG, Krebs von den Lungen-6, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Peanut-reactive urinary mucin
Anti-MUC1 Monoclonal Antibody is a rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody can be used in ELISA, FACS.
Anti-MUC1 Monoclonal Antibody
Anti-MUC1 Monoclonal Antibody
产品编号 TMAZ-0113 别名 PEMT, Carcinoma-associated mucin, Tumor-associated mucin, Episialin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3, Mucin-1, H23AG, Krebs von den Lungen-6, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Peanut-reactive urinary mucin
Anti-MUC1 Monoclonal Antibody is a rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 958 | 7日内发货 | |
| 50 μg | ¥ 1,149 | 7日内发货 | |
| 100 μg | ¥ 1,608 | 7日内发货 |
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偶联与修饰
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| 产品描述 | Anti-MUC1 Monoclonal Antibody is a rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | PEMT, Carcinoma-associated mucin, Tumor-associated mucin, Episialin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3, Mucin-1, H23AG, Krebs von den Lungen-6, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Peanut-reactive urinary mucin |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of MUC1 overexpressed 395F cells with TMAZ-0113, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MUC1 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | MUC1 |
| 抗原种属 | Human |
| 基因ID | 4582 |
| Uniprot ID | |
| 研究领域 | Cancer Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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