Prinomastat hydrochloride

Name: Prinomastat hydrochloride
Brand: TargetMol
SKU: T12539
Price: 123 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T12539Cas号 1435779-45-5

别名 KB-R9896 hydrochloride, AG3340 hydrochloride

Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.

Prinomastat hydrochloride

还可以

产品编号 T12539 别名 KB-R9896 hydrochloride, AG3340 hydrochlorideCas号 1435779-45-5

Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.

规格	价格	库存
25 mg	¥ 10,500	1-2周
50 mg	¥ 13,700	1-2周
100 mg	¥ 17,400	1-2周

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.
靶点活性	MMP9:0.26 nM (ki), MMP9:5 nM, MMP13:0.3 nM (ki), MMP13:6.3 nM, MMP2:0.05 nM (ki), MMP1:79 nM
体外活性	Prinomastat inhibits Wnt1-induced MMP-3 production. Reversal of Wnt1-induced EMT and β-catenin transcriptional activity by Prinomastat[1].
体内活性	Prinomastat has good tumour growth inhibition, with a short T1/2 of 1.6 hours[1].
别名	KB-R9896 hydrochloride, AG3340 hydrochloride

化学信息

分子量	459.97
分子式	C₁₈H₂₂ClN₃O₅S₂
CAS No.	1435779-45-5
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (217.41 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1741 mL	10.8703 mL	21.7405 mL	108.7027 mL
5 mM	0.4348 mL	2.1741 mL	4.3481 mL	21.7405 mL
10 mM	0.2174 mL	1.0870 mL	2.1741 mL	10.8703 mL
20 mM	0.1087 mL	0.5435 mL	1.0870 mL	5.4351 mL
50 mM	0.0435 mL	0.2174 mL	0.4348 mL	2.1741 mL
100 mM	0.0217 mL	0.1087 mL	0.2174 mL	1.0870 mL