Aphidicolin

Name: Aphidicolin
Brand: TargetMol
SKU: T14304
Price: 1230 USD
Availability: InStock
Rating: 5 (10 reviews)

很棒

产品编号 T14304Cas号 38966-21-1

别名 阿非迪霉素

Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA polymerase[1] and is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

Aphidicolin

很棒

产品编号 T14304 别名 阿非迪霉素Cas号 38966-21-1

规格	价格	库存	数量
1 mg	¥ 1,230	现货

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产品介绍

生物活性

产品描述

Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

别名

阿非迪霉素

化学信息

分子量	338.48
分子式	C₂₀H₃₄O₄
CAS No.	38966-21-1
Smiles	[H][C@]12C[C@]3([H])C[C@]1(CC[C@]3(O)CO)[C@@]1(C)CC[C@@H](O)[C@@](C)(CO)[C@]1([H])CC2
密度	1.31g/cm3