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Vesnarinone (Arkin) 是一种喹啉酮衍生物,可抑制磷酸二酯酶III 活性,增加钙通量和减小钾通量。
Vesnarinone (Arkin) 是一种喹啉酮衍生物,可抑制磷酸二酯酶III 活性,增加钙通量和减小钾通量。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 208 | 现货 | |
5 mg | ¥ 497 | 现货 | |
10 mg | ¥ 738 | 现货 | |
25 mg | ¥ 1,180 | 现货 | |
50 mg | ¥ 2,230 | 现货 | |
100 mg | ¥ 3,730 | 现货 | |
200 mg | ¥ 4,960 | 现货 |
产品描述 | Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest. |
靶点活性 | PDE3:1.1 μM |
别名 | 维司力农, Piteranometozine, OPC-8212, Arkin |
分子量 | 395.45 |
分子式 | C22H25N3O4 |
CAS No. | 81840-15-5 |
Smiles | COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1 |
密度 | 1.246g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
溶解度信息 | DMSO: 3.95 mg/mL (9.99 mM), Sonication is recommended. | |||||||||||||||
溶液配制表 | ||||||||||||||||
DMSO
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