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Trimetazidine, an anti-ischemic (anti-anginal) metabolic agent, could improve myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.
Trimetazidine, an anti-ischemic (anti-anginal) metabolic agent, could improve myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.
产品描述 | Trimetazidine, an anti-ischemic (anti-anginal) metabolic agent, could improve myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation. |
靶点活性 | HADHA:3-hydroxyacyl-CoA dehydrogenase , Long chain 3-ketoyl coenzyme A thiolase:75 nM (IC50) |
别名 | 曲美他嗪 |
分子量 | 266.3361 |
分子式 | C14H22N2O3 |
CAS No. | 5011-34-7 |
密度 | 1.092 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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