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Pomalidomide-6-O-CH3
还可以产品编号 T39033Cas号 1547163-08-5
别名 Pomalidomide-6-O-CH3
Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
Pomalidomide-6-O-CH3
还可以产品编号 T39033 别名 Pomalidomide-6-O-CH3Cas号 1547163-08-5
Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 10,600 | 期货 |
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生物活性
化学信息
| 产品描述 | Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC. |
| 体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| 别名 | Pomalidomide-6-O-CH3 |
| 分子量 | 303.274 |
| 分子式 | C14H13N3O5 |
| CAS No. | 1547163-08-5 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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