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Guanosine 5'-diphosphate ditromethamine(GDP ditromethamine)作为一种核苷二磷酸,能够激活5'-三磷酸腺苷敏感的K+通道。此外,此化合物是一种有效的铁动员剂,其通过阻断铁调素-铁转运蛋白(hepcidin-ferroportin)相互作用,并可调节IL-6/stat-3通路,进而在炎症性贫血(AI)等炎症研究中发挥重要作用。
Guanosine 5'-diphosphate ditromethamine(GDP ditromethamine)作为一种核苷二磷酸,能够激活5'-三磷酸腺苷敏感的K+通道。此外,此化合物是一种有效的铁动员剂,其通过阻断铁调素-铁转运蛋白(hepcidin-ferroportin)相互作用,并可调节IL-6/stat-3通路,进而在炎症性贫血(AI)等炎症研究中发挥重要作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Guanosine 5'-diphosphate ditromethamine (GDP ditromethamine) is a nucleoside diphosphate that activates ATP-sensitive K+ channels. It acts as a potential iron mobilizer, inhibiting the interaction between hepcidin and ferroportin, and modulating the IL-6/STAT-3 pathway. This compound finds application in inflammation research, such as studying anemia of inflammation (AI). |
别名 | GDP ditromethamine |
分子量 | 685.47 |
分子式 | C18H37N7O17P2 |
CAS No. | 103192-39-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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