C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a sulfated glycolipid.C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice.C16 3'-sulfo Galactosylceramide is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice.C16 3'-sulfo Galactosylceramide is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development in mice. C16 3'-sulfo Galactosylceramide (d18:1/16:0) inhibits retinal ganglion cell growth in vitro.C16 3'-sulfo Galactosylceramide (d18:1/16:0) has been used as an internal standard for quantifying C16 3'-sulfo Galactosylceramide (d18:1/16:0) in rat cerebellum and white matter isolated from patients with multiple sclerosis. reference for sulphides.

C16:0 sulfatide（20 nmol/ml）通过降低K(ATP)通道对ATP的敏感性，抑制了由葡萄糖刺激引起的胰岛素分泌。（在没有C16:0 sulfatide和存在C16:0 sulfatide的情况下，半最大抑制浓度分别为10.3和36.7 micromol/l。）[1] C16:0 sulfatide（20 nmol/ml，持续30分钟）在中等葡萄糖水平下增加了全细胞K(ATP)电流，降低了葡萄糖诱导的膜去极化能力，减少了电活动，并增加了细胞质内游离Ca2+浓度。细胞电容记录显示，C16:0 sulfatide通过215%增加了Ca2+诱导的胞吐作用，这与C16:0 sulfatide在暴露于二氮嗪和高K+的完整大鼠岛细胞中刺激胰岛素分泌相相关。[1] C16:0 sulfatide（20 nmol/l，持续24小时）未对完整大鼠岛细胞中的胰高血糖素分泌产生调节作用。[1]

C16:0 sulfatide（1 µmol/kg，1 mL；Zucker 大鼠）显著提高了葡萄糖刺激下的胰岛素分泌（增加了60-80%，p < 0.05），但对葡萄糖耐量没有显著影响。此治疗与第一相胰岛素反应的改善（增加3-4倍，p = 0.009, 0.016）以及胰腺硫酸酯含量增加60%（p = 0.001）有关，可能是由于对C16:0硫酸酯的吸收。禁食时的高胰岛素血症和血糖水平未发生变化。[2]