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顶部产品介绍化学信息储存和溶解信息计算器技术支持

PMVK Protein, Human, Recombinant (His)

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货号 TMPY-04767

别名 PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI

PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

PMVK Protein, Human, Recombinant (His)

PMVK Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 还可以
货号 TMPY-04767 别名 PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI

PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

规格价格库存数量
5 μg
¥ 472
6-8日内发货
10 μg
¥ 772
6-8日内发货
20 μg
¥ 1,270
5日内发货
50 μg
¥ 2,930
5日内发货
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产品介绍

生物活性
产品描述
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
生物活性
Kinase activity untested
研究背景
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
种属
Human
表达系统
E. coli
标签N-His
蛋白编号Q15126
蛋白构建A DNA sequence encoding the mature form of human PMVK(Q15126) (Met1-Leu192) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
蛋白纯度
> 90 % as determined by SDS-PAGE
蛋白性状Solution
缓冲液Supplied as sterile 50 mM MOPS, 150 mM KCl, 1 mM DTT, pH 7.0.
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI
内毒素Please contact us for more information.
化学信息
分子量23.8 kDa (predicted); 24 kDa (reducing conditions)
储存&溶解度
运输方式Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
存储It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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