RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M. separata and P. xylostella. It exhibits an LC50 of 3.27 mg/L for controlling diamondback moth populations. The mechanism of action involves binding to the ryanodine receptor, which elevates cytoplasmic Ca2+ concentration, resulting in biological toxicity [1].