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Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology.
Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥ 3,320 | 期货 | |
100 mg | ¥ 5,390 | 期货 | |
500 mg | ¥ 13,700 | 期货 |
产品描述 | Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
别名 | Pomalidomide-PEG3-azide |
分子量 | 488.457 |
分子式 | C21H24N6O8 |
CAS No. | 2267306-15-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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