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12(S)-HEPE
还可以产品编号 T37967Cas号 116180-17-7
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
12(S)-HEPE
还可以产品编号 T37967Cas号 116180-17-7
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | 待估 | 35日内发货 | |
| 50 μg | 待估 | 35日内发货 | |
| 100 μg | 待估 | 35日内发货 |
大包装 & 定制
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产品介绍
生物活性
化学信息
| 产品描述 | 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids. |
| 分子量 | 318.45 |
| 分子式 | C20H30O3 |
| CAS No. | 116180-17-7 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| 溶解度信息 | 0.1 M Na2CO3: 2 mg/mL (6.28 mM), Sonication is recommended. DMF: Miscible DMSO: Miscible PBS (pH 7.2): 0.8 mg/mL (2.51 mM), Sonication is recommended. Ethanol: Miscible | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
PBS (pH 7.2)/0.1 M Na2CO3
0.1 M Na2CO3
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