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Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.
Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 μg | ¥ 2,670 | 35日内发货 | |
25 μg | ¥ 6,330 | 35日内发货 | |
50 μg | ¥ 11,900 | 35日内发货 | |
100 μg | ¥ 19,800 | 35日内发货 |
产品描述 | Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation. |
体外活性 | RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells[2]. |
体内活性 | Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1]. Animal Model: Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1]Dosage: 100 ng/100 μl Administration: IP; daily for 6 days Result: Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis. |
别名 | RvD3 |
分子量 | 376.493 |
分子式 | C22H32O5 |
CAS No. | 916888-47-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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