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(±)14(15)-EpETE是一种含有环氧基团的二十碳四烯酸衍生物,是肠道微生物脂质代谢物,通过靶向GCG/PKA信号抑制Substance P释放减轻大鼠顺铂化疗诱导的恶心和呕吐,通常用于研究炎症和代谢。
(±)14(15)-EpETE是一种含有环氧基团的二十碳四烯酸衍生物,是肠道微生物脂质代谢物,通过靶向GCG/PKA信号抑制Substance P释放减轻大鼠顺铂化疗诱导的恶心和呕吐,通常用于研究炎症和代谢。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | 待估 | 35日内发货 | |
50 μg | ¥ 2,230 | 35日内发货 | |
100 μg | 待估 | 35日内发货 | |
500 μg | 待估 | 35日内发货 |
产品描述 | (±)14(15)-EpETE, an eicosatetraenoic acid derivative containing an epoxy group, is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea and vomiting in rats by inhibiting Substance P release through targeting GCG/PKA signaling and is commonly used to study inflammation and metabolism. |
别名 | 14(15)-EpETE |
分子量 | 318.45 |
分子式 | C20H30O3 |
CAS No. | 131339-24-7 |
Smiles | C(/C=C\C/C=C\C/C=C\CCCC(O)=O)[C@H]1[C@@H](C/C=C\CC)O1 |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 10 mg/mL (31.4 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL (3.14 mM), Sonication is recommended. Ethanol: 10 mg/mL (31.4 mM), Sonication is recommended. DMF: 10 mg/mL (31.4 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMSO/Ethanol/DMF
DMSO/Ethanol/DMF
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