SPR inhibitor 3

Name: SPR inhibitor 3
Brand: TargetMol
SKU: T16924
Price: 272 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T16924Cas号 1292285-54-1

别名 SPRi3

SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM).

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SPR inhibitor 3

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产品编号 T16924 别名 SPRi3Cas号 1292285-54-1

规格	价格	库存
2 mg	¥ 642	5日内发货
5 mg	¥ 1,080	5日内发货
10 mg	¥ 1,530	5日内发货
25 mg	¥ 3,150	5日内发货
50 mg	¥ 6,220	5日内发货
1 mL x 10 mM (in DMSO)	¥ 1,180	5日内发货

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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM).
靶点活性	Sepiapterin reductase:74 nM
体外活性	SPR inhibitor 3 obviously decreases SPR activity in mouse primary cultures of sensory neurons (IC50=0.45 μM) without affecting the activity of the GTP cyclohydroxylase 1 enzyme [1].
别名	SPRi3