Ibiglustat succinate

Name: Ibiglustat succinate
Brand: TargetMol
SKU: T39105
Price: 720 USD
Availability: InStock
Rating: 4.5 (1 reviews)

产品编号 T39105Cas号 1629063-80-4

别名 Venglustat succinate, SAR402671succinate, Ibiglustat succinate, GZ402671succinate

Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.

Ibiglustat succinate

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产品编号 T39105 别名 Venglustat succinate, SAR402671succinate, Ibiglustat succinate, GZ402671succinateCas号 1629063-80-4

规格	价格	库存	数量
2 mg	¥ 1,180	5日内发货
5 mg	¥ 1,990	5日内发货

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产品介绍

生物活性

产品描述	Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
体外活性	Ibiglustat (SAR402671) succinate (1 μM, 15 days; Fabry disease (FD) cells) is close to the physiological level in untreated WT cells in GL-3 levels, suggesting that Ibiglustat succinate can prevent additional GL-3 accumulation and could serve to ameliorate the abundant levels of this sphingolipid in FD cardiomyocytes[4].
别名	Venglustat succinate, SAR402671succinate, Ibiglustat succinate, GZ402671succinate