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VICENISTATIN是一种新型化合物,能够促使早期内体的囊泡化。通过激活Rab5-PAS通路并增加膜流动性,VICENISTATIN诱导类似囊泡的结构生成。作为抗肿瘤抗生素,该化合物在异种移植模型中对人类结肠癌Co-3表现出抗肿瘤活性。
VICENISTATIN是一种新型化合物,能够促使早期内体的囊泡化。通过激活Rab5-PAS通路并增加膜流动性,VICENISTATIN诱导类似囊泡的结构生成。作为抗肿瘤抗生素,该化合物在异种移植模型中对人类结肠癌Co-3表现出抗肿瘤活性。
产品描述 | VICENISTATIN is a novel compound capable of inducing the vesiculation of early endosomes. It promotes the formation of vesicle-like structures by activating the Rab5-PAS pathway and enhancing membrane fluidity. Additionally, VICENISTATIN functions as an antitumor antibiotic, demonstrating antitumor activity against human colon cancer Co-3 in xenograft models. |
别名 | Vicenistatine, NSC-641691 |
分子量 | 500.71 |
分子式 | C30H48N2O4 |
CAS No. | 150999-05-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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