Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC(50) value of 10.0 μM as determined by an ELISA assay, and 2.5 μM in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.
Blapsin B
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产品编号 T68529Cas号 861145-00-8
Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC(50) value of 10.0 μM as determined by an ELISA assay, and 2.5 μM in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.
Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC(50) value of 10.0 μM as determined by an ELISA assay, and 2.5 μM in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.
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