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PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
还可以产品编号 T37028Cas号 1628353-02-5
别名 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
还可以产品编号 T37028 别名 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)Cas号 1628353-02-5
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 822 | 35日内发货 | |
| 500 μg | ¥ 3,600 | 35日内发货 | |
| 1 mg | ¥ 6,300 | 35日内发货 | |
| 5 mg | ¥ 27,400 | 35日内发货 |
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| 产品描述 | The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. |
| 别名 | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) |
| 分子量 | 1138.9 |
| 分子式 | C41H78Na4O22P4 |
| CAS No. | 1628353-02-5 |
| 密度 | no data available |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/mL PBS (pH 7.2): 10 mg/mL |
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