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COX-2/5-LOX-IN-3
还可以产品编号 T61352Cas号 2481484-51-7
COX-2/5-LOX-IN-3 (compound 5b) is a powerful and dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. This compound, COX-2/5-LOX-IN-3, shows promise for the investigation of inflammatory diseases [1].
COX-2/5-LOX-IN-3
还可以产品编号 T61352Cas号 2481484-51-7
COX-2/5-LOX-IN-3 (compound 5b) is a powerful and dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. This compound, COX-2/5-LOX-IN-3, shows promise for the investigation of inflammatory diseases [1].
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 10,600 | 6-8周 | |
| 50 mg | ¥ 13,800 | 6-8周 | |
| 100 mg | ¥ 17,500 | 6-8周 |
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| 产品描述 | COX-2/5-LOX-IN-3 (compound 5b) is a powerful and dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. This compound, COX-2/5-LOX-IN-3, shows promise for the investigation of inflammatory diseases [1]. |
| 体内活性 | COX-2/5-LOX-IN-3 (compound 5b) (p.o.; male Sprague Dawley rats) shows anti-inflammatory activities in vivo [1]. Animal Model: Male Sprague Dawley rats [1] Dosage: 2.622 X 10 -5 mol/kg Administration: Oral administration Result: The percentage inhibition of edema (%I) reached 58.77% after 4h. |
| 分子量 | 361.85 |
| 分子式 | C17H16ClN3O2S |
| CAS No. | 2481484-51-7 |
储存&溶解度
| 存储 | Shipping with blue ice. |
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