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Pomalidomide-amino-PEG3-NH2 is a compound obtained through synthesis, consisting of a conjugation between the E3 ligase ligand linker and Pomalidomide, a cereblon ligand. This compound is specifically designed for application in PROTAC technology, incorporating a linker that enables effective binding with the targeted proteins.
Pomalidomide-amino-PEG3-NH2 is a compound obtained through synthesis, consisting of a conjugation between the E3 ligase ligand linker and Pomalidomide, a cereblon ligand. This compound is specifically designed for application in PROTAC technology, incorporating a linker that enables effective binding with the targeted proteins.
规格 | 价格 | 库存 | 数量 |
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100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | Pomalidomide-amino-PEG3-NH2 is a compound obtained through synthesis, consisting of a conjugation between the E3 ligase ligand linker and Pomalidomide, a cereblon ligand. This compound is specifically designed for application in PROTAC technology, incorporating a linker that enables effective binding with the targeted proteins. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
别名 | Pomalidomide-amino-PEG3-NH2 |
分子量 | 462.459 |
分子式 | C21H26N4O8 |
CAS No. | 2380273-74-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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