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(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride 作为一种重要的脂质类化合物,主要用于构建脂质体。脂质体是由同心磷脂双层膜构成的囊泡结构,广泛应用于抗癌和抗感染药物的递送系统。该化合物能够实现高极性水溶性载荷在脂质体内部水性空间的有效捕获,同时亲脂性载荷可以整合进磷脂双层。此外,它特别适用于反义寡核苷酸的递送,有效解决了细胞内摄取效率低和体内快速流失的问题。
(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride 作为一种重要的脂质类化合物,主要用于构建脂质体。脂质体是由同心磷脂双层膜构成的囊泡结构,广泛应用于抗癌和抗感染药物的递送系统。该化合物能够实现高极性水溶性载荷在脂质体内部水性空间的有效捕获,同时亲脂性载荷可以整合进磷脂双层。此外,它特别适用于反义寡核苷酸的递送,有效解决了细胞内摄取效率低和体内快速流失的问题。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | (2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride is a lipid compound utilized in the preparation of liposomes. Liposomes, characterized by concentric phospholipid bilayer vesicles, are critical in constructing drug delivery systems for anti-cancer and anti-infection applications. They effectively encapsulate hydrophilic solutes within their aqueous interiors and incorporate lipophilic cargoes into their phospholipid bilayers, making them integral to the bilayer structure. This compound is particularly valuable in delivering antisense oligonucleotides, addressing challenges such as inefficient cellular uptake and rapid loss in the body. |
别名 | (2S)-3-Keto-C6-dihydrosphingosine hydrochloride |
分子量 | 167.63 |
分子式 | C6H14ClNO2 |
CAS No. | 1314999-30-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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