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Targets Recommended: Wnt/beta-catenin

3023

抑制剂 & 化合物

479

天然产物

33

化合物库

6823

重组蛋白

62

同位素标记化合物

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Cat. No. Product Name
L9410 共价抑制剂库

1920 compounds
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;
L2500 人内源代谢化合物库

499 compounds
499 种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选;
L2570 人代谢物化合物库

4454 compounds
4454 种人代谢物的独特集合,用于高通量、高内涵筛选;
L2540 肠道微生物代谢化合物库

614 compounds
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选;
L1380 转录因子库

695 compounds
695 种转录因子靶向、结构新颖的化合物;
L9400 PPI抑制剂库

485 compounds
485 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选;
L4660 神经疾病库Plus

1246 compounds
1246 种神经系统相关、结构新颖的化合物;
L1580 GPCR库Plus

338 compounds
338 种GPCR 靶向、结构新颖的化合物;
L7000 活性脂质化合物库

385 compounds
385 种生物活性小分子化合物,用于高通量、高内涵筛选;
L1500 GPCR靶点分子库

1940 compounds
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物;
L8700 铁死亡化合物库

779 compounds
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L2300 离子通道库

931 compounds
931 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选;
L2100 抗癌化合物库

7234 compounds
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L8200 抗衰老化合物库

3279 compounds
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2180 抗肿瘤库Plus

1468 compounds
1468 种抗肿瘤相关、结构新颖的化合物;
L2160 抗癌活性化合物库

3188 compounds
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
L2150 抗癌药物库

3080 compounds
3080 个具有抗癌活性小分子的独特集合,生物活性已经临床前实验证实,可用于高通量、高内涵筛选;
L2501 人内源代谢化合物库 Plus

1283 compounds
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。
L7200 钙通道分子库

140 compounds
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L9000 细胞凋亡化合物库

1760 compounds
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选;
L8300 染色质修饰分子库

250 compounds
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2120 抗癌临床化合物库

2545 compounds
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。
L2191 抗乳腺癌化合物库

1939 compounds
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究;
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L2110 抗癌上市药物库

1779 compounds
1779 个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA 或NMPA 批准上市,可用于高通量、高内涵筛选。
L4300 Wnt/Hedgehog/Notch 通路化合物库

237 compounds
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。
L9600 多肽分子库

791 compounds
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究;
L6820 烟草单体化合物库

747 compounds
747种烟草单体化合物的独特集合,可用于高通量筛选和高内涵筛选
L1800 抗感染化合物库

2938 compounds
2938 种具有抗感染活性的化合物的特有集合,包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性;
L1710 抗COVID-19化合物库

1133 compounds
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;
L6500 微生物天然产物库

685 compounds
685 种微生物来源的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2194 抗结直肠癌化合物库

1545 compounds
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选;
DO1200 药物靶点库

53200 compounds
数量多,含53200种小分子化合物,是高通量筛选的有力工具;

化合物库

共价抑制剂库
Cat.No: L9410
Compounds: 1920
人内源代谢化合物库
Cat.No: L2500
Compounds: 499
人代谢物化合物库
Cat.No: L2570
Compounds: 4454
肠道微生物代谢化合物库
Cat.No: L2540
Compounds: 614
转录因子库
Cat.No: L1380
Compounds: 695
PPI抑制剂库
Cat.No: L9400
Compounds: 485
神经疾病库Plus
Cat.No: L4660
Compounds: 1246
GPCR库Plus
Cat.No: L1580
Compounds: 338
活性脂质化合物库
Cat.No: L7000
Compounds: 385
GPCR靶点分子库
Cat.No: L1500
Compounds: 1940
铁死亡化合物库
Cat.No: L8700
Compounds: 779
离子通道库
Cat.No: L2300
Compounds: 931
抗癌化合物库
Cat.No: L2100
Compounds: 7234
抗衰老化合物库
Cat.No: L8200
Compounds: 3279
抗肿瘤库Plus
Cat.No: L2180
Compounds: 1468
抗癌活性化合物库
Cat.No: L2160
Compounds: 3188
抗癌药物库
Cat.No: L2150
Compounds: 3080
人内源代谢化合物库 Plus
Cat.No: L2501
Compounds: 1283
钙通道分子库
Cat.No: L7200
Compounds: 140
细胞凋亡化合物库
Cat.No: L9000
Compounds: 1760
染色质修饰分子库
Cat.No: L8300
Compounds: 250
抗癌临床化合物库
Cat.No: L2120
Compounds: 2545
抗乳腺癌化合物库
Cat.No: L2191
Compounds: 1939
黄酮类天然产物库
Cat.No: L6120
Compounds: 514
抗癌上市药物库
Cat.No: L2110
Compounds: 1779
Wnt/Hedgehog/Notch 通路化合物库
Cat.No: L4300
Compounds: 237
多肽分子库
Cat.No: L9600
Compounds: 791
烟草单体化合物库
Cat.No: L6820
Compounds: 747
抗感染化合物库
Cat.No: L1800
Compounds: 2938
抗COVID-19化合物库
Cat.No: L1710
Compounds: 1133
微生物天然产物库
Cat.No: L6500
Compounds: 685
抗结直肠癌化合物库
Cat.No: L2194
Compounds: 1545
药物靶点库
Cat.No: DO1200
Compounds: 53200
Cat. No. Product Name Target Signaling Pathways
T2052 KY02111

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
KY02111 是典型的 WNT 信号抑制剂,能够促进人多潜能干细胞向心肌细胞分化,可用于研究人类心肌细胞再生。
T1883 Des(benzylpyridyl) Atazanavi

HIV Protease Microbiology/Virology; Proteases/Proteasome
Des(benzylpyridyl) Atazanavi 是 Atazanavir 的 N-脱烷基代谢物 (M1),一种 HIV 蛋白酶抑制剂。
T0100L Atazanavir

Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632

P450; SARS-CoV; HIV Protease; P-gp Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂,可研究艾滋病毒感染。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 3.49 μM。它是CYP3A4的底物和抑制剂,也是P-糖蛋白的抑制剂和诱导剂。
T0100 Atazanavir sulfate

阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

P450; SARS-CoV; HIV Protease; P-gp Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂,与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂,IC50为 3.49 μM。
TP2018L GIP (human) acetate

GIP (human) acetate(100040-31-1 Free base)

IGF-1R Tyrosine Kinase/Adaptors
GIP (human) acetate 是葡萄糖依赖性胰岛素分泌的刺激剂和胃酸分泌的弱抑制剂。 GIP (human) acetate 在脂质代谢和肥胖的发展中起着至关重要的作用。
TP1949L PEN (human) aceate

GPCR19 GPCR/G Protein
PEN (human) aceate 是丰富的下丘脑神经肽之一,源自 ProSAAS 前蛋白,是 GPR83 的内源性配体。
TP1143L Fibrinopeptide A, human acetate

Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate

Others Others
Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽,由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。
TP1900L1 Hemopressin (human, mouse) acetate

Hemopressin (human, mouse) acetate(1314035-51-2 free base)

Cannabinoid Receptor GPCR/G Protein
Hemopressin (human, mouse) acetate(1314035-51-2 free base) 是一种衍生自血红蛋白 α1 链的九肽,是从大鼠脑匀浆中分离出来的。 Hemopressin 是 CB1 大麻素受体的口服活性、选择性和反向激动剂。 Hemopressin 在炎性疼痛模型中发挥镇痛作用。
TP1899L1 Hemokinin 1 (human) acetate(491851-53-7 free base)

Neurokinin receptor GPCR/G Protein; Neuroscience
Hemokinin 1 (human) acetate(491851-53-7 free base) 是一种内源性 P 物质同系物,是速激肽 NK1 受体的选择性激动剂(NK1、NK3 和 NK2 受体的 IC50 值分别为 1.8、370 和 480 nM)。在体外对 B 细胞具有增殖和抗凋亡作用,在体内具有抗高血压作用。
T36926L Neuropeptide SF (human) aceate

Others Others
Neuropeptide SF (human) aceate 是一种神经肽,可增强心室旁 CRH 的释放并增加血浆中的 ACTH 和皮质酮水平。
TP1137L Pancreatic Polypeptide (human) acetate

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Pancreatic Polypeptide (human) acetate 是一种 C 末端酰胺化的 36 个氨基酸肽,可作为神经肽 Y (NPY) Y4/Y5 受体激动剂。
TP1936L1 RFRP3(human) acetate(311309-27-0 free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
RFRP3(human) acetate(311309-27-0 free base) 是一种人类 GnIH 肽同源物,是一种有效的促性腺激素分泌抑制剂,可抑制 Ca2+ 动员。它是一种 NPFF1 受体激动剂,它抑制毛喉素诱导的 cAMP 产生,IC50 为 0.7 nM。
TP2312 MOTS-c(Human) Acetate(1627580-64-6 free)

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
MOTS-c(Human) Acetate(1627580-64-6 free)是一种线粒体衍生肽。 它诱导 AMP 类似物 AICAR 的积累,增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。 它对调节肥胖、糖尿病、运动和长寿有重要意义。
TP1821L Mini Gastrin I, human acetate

cholecystokinin GPCR/G Protein
Mini Gastrin I, human acetate 是人胃泌素的较短版本,由母肽的氨基酸 5-17 组成。
TP1835L Enterostatin, human, mouse, rat acetate

Endogenous Metabolite Metabolism
Enterostatin, human, mouse, rat acetate 是一种五肽,主要由分泌的胰腺前脂肪酶在肠道中形成。
TP1775L LL-37, Human acetate(154947-66-7 free base)

Antibacterial Microbiology/Virology
LL-37, Human acetate(154947-66-7 free base) 是一种 37 个残基、两亲性、cathelicidin 衍生的抗菌肽,具有广谱的抗菌活性。
TP1922L1 ELA-11 (human) acetate(1784687-32-6 free base)

Apelin receptor; Arrestin GPCR/G Protein
ELA-11 (human) acetate(1784687-32-6 free base)是亲和力 apelin 受体激动剂 (Ki = 14 nM)。 ELA-32 的生物活性片段。在体外抑制毛喉素诱导的 cAMP 产生并刺激 β-arrestin 募集。
TP1923L1 ELA-14(human) acetate

ELA-14(human) acetate (1886973-05-2 free base)

Apelin receptor; Arrestin GPCR/G Protein
ELA-14(human) acetate 是 ELA 的一个片段,它与 APJ 结合,激活 Gαi1 和 β-arrestin-2 信号通路,并类似于其亲本内源性肽诱导受体内化。
TP1187 C-Type Natriuretic Peptide (CNP) (1-22), human

CNP (1-22), human

RAAS Endocrinology/Hormones
C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂,是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
TP1073 Neuropeptide W-23(human)

NPW-23

Others Others
Neuropeptide W-23(human) (NPW-23) 是 NPBW1 和 NPBW2 的内源性配体,是 Neuropeptide W 的主要活性形式。
TP1345 Kisspeptin-10, human (TFA)(374675-21-5,FREE)

GPR; Kisspeptin Endocrinology/Hormones; GPCR/G Protein
Kisspeptin-10, human (TFA)(374675-21-5,FREE) 是一种有效的血管收缩剂和血管生成抑制剂。 Kisspeptin-10,人类 TFA 通过其受体 GPR54 充当肿瘤转移抑制因子。 Kisspeptin-10-GPR54系统在胚胎肾发育中发挥重要作用。 Kisspeptin-10/GPR54 信号通过 NFATc4 介导的 BMP2 表达诱导成骨细胞分化
T19309L1 Endothelin 1 (swine, human) acetate

Endothelin 1 (swine, human) acetate(117399-94-7 free base)

Endothelin Receptor GPCR/G Protein
Endothelin 1 (swine, human) acetate(117399-94-7 free base) 是一种合成肽,其序列为人和猪内皮素 1。它是一种有效的内源性血管收缩剂,通过两种类型的受体 ETA 和 ETB 起作用。
TP1937L1 RFRP-1 (human) acetate(311309-25-8 free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
RFRP-1 (human) acetate(311309-25-8 free base) 是一种有效的内源性 NPFF 受体激动剂(NPFF2 和 NPFF1 的 EC50 值分别为 0.0011 和 29 nM)。它减弱离体大鼠和兔心肌细胞的收缩功能。降低心率、每搏输出量、射血分数和心输出量,并增加大鼠的血浆催乳素水平。 GnIH 同系物。
TP1188L Cortistatin 14, human, rat acetate

Somatostatin GPCR/G Protein
Cortistatin 14, human, rat acetate 是一种与 somatostatin-14 结构相似的神经肽,具有抗惊厥、神经保护作用和显着的抗炎特性。 Cortistatin 14, human, rat acetate 通过与生长抑素受体结合并发挥其功能。
TP1705 Gastrin I (1-14), human

Others Others
Gastrin I (1-14), human 是人胃泌素 I 肽的 1-14 片段。其中Gastrin I 是内源性胃肠肽激素。Gastrin 是胃酸分泌的主要激素调节剂。
T38193L β-Endorphin (1-27) (human) acetate

β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
β-Endorphin (1-27) (human) acetate 存在于大脑垂体和下丘脑中,具有镇痛活性。 β-Endorphin (1-27) (human) acetate 是一种阿片受体激动剂,对 μ-阿片受体和 δ-阿片受体具有较好的亲和力。
T40412L BAD (103-127) (human) acetate

BAD (103-127) (human) acetate (331762-68-6 Free base)

Others Others
BAD (103-127) (human) acetate 是一种来自于 BAD 的 BH3结构域的25-mer Bad 多肽,可拮抗 Bcl-xl 的作用。
TP1842L Angiotensinogen (1-14), human acetate

Endogenous Metabolite Metabolism
Angiotensinogen (1-14), human acetate 是血管紧张素原的片段,它是肾素-血管紧张素系统的被动底物。
TP1880L1 PAMP-12 (human, porcine) acetate

PAMP-12 (human, porcine) acetate(196305-05-2 free base)

Others Others
PAMP-12 (human, porcine) acetate (PAMP-12 (human, porcine) acetate (196305-05-2 free base)) 是 ir-PAMP 的主要成分,由 AM 前体加工而成,PAMP-20 也是如此,并且可能参与心血管控制。
TP1863L Glucagon (19-29), human acetate

Glucagon Receptor GPCR/G Protein
Glucagon (19-29), human acetate 是一种从胰高血糖素加工而来的 COOH 末端片段,是一种有效的胰岛素分泌抑制剂。
TP1144L Corticotropin-releasing factor (human) acetate

Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)

CRFR GPCR/G Protein
Corticotropin-releasing factor (human) acetate 刺激垂体前叶合成和分泌促肾上腺皮质激素。
TP2092L Apelin-17 (human, bovine) acetate

Apelin-17 (human, bovine) acetate(217082-57-0 free base)

HIV Protease Microbiology/Virology; Proteases/Proteasome
Apelin-17 (human, bovine) acetate(217082-57-0 free base) 是一种内源性 apelin 受体激动剂。有效抑制毛喉素刺激的 cAMP 积累 (pIC50 = 9.94)。
TP1453 Tau protein (592-597), Human TFA

Others Others
Tau protein (592-597), Human TFA 是人 Tau 蛋白的肽片段。
T19584L TNF-α (31-45), human acetate

TNF-α (31-45), human acetate(144796-71-4 free base)

Others Others
TNF-α (31-45), human acetate(144796-71-4 free base) 是一种肿瘤坏死因子-α 的肽。
TP1257L Adrenomedullin (AM) (22-52), human acetate

Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base)

CGRP Receptor GPCR/G Protein; Neuroscience
Adrenomedullin (AM) (22-52), human acetate 是猫后肢血管床中 CGRP 受体和肾上腺髓质素受体的拮抗剂。
T7489 MART-1 (26-35) (human)

MART-1 (26-35) human

Others Others
MART-1 (26-35) (human) (MART-1 (26-35) human) 是一种 MART-1 蛋白 26 到 35 氨基酸片段。
TP1155L Human growth hormone-releasing factor acetate

GHSR GPCR/G Protein
Human growth hormone-releasing factor acetate 是一种下丘脑多肽,通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。
TP1059 Peptide YY (PYY) (3-36), human

Peptide YY (3-36)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) 是一种肠胃激素肽,可以激动Y2受体,具有降低食欲的功效。
TP1140L Neuropeptide Y (29-64), amide, human acetate

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Neuropeptide Y (29-64), amide, human acetate 参与阿尔茨海默病 (AD) 并保护大鼠皮质神经元免受 β-淀粉样蛋白毒性。
T78339 Human IgG4 (S228P) kappa, Isotype Control

Others Others
Human IgG4 (S228P) kappa, Isotype Control是人-鼠嵌合型抗体,可用研究自身免疫疾病。
TP1283L VIP(6-28)(human, rat, porcine, bovine) acetate

Others Others
VIP(6-28)(human, rat, porcine, bovine) acetate 是外源性血管活性肠肽 (VIP) 受体对颈上神经节 (SCG) 中 cAMP 作用的拮抗剂。
TP1618L PACAP-38 (31-38), human, mouse, rat acetate

PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)

PACAP GPCR/G Protein
PACAP-38 (31-38), human, mouse, rat acetate 是 PAC1 受体的激活剂。PACAP-38 (31-38), human, mouse, rat acetate 对交感神经元 NPY 和儿茶酚胺的产生具有强效、有效和持续的刺激作用,可用于神经营养和神经保护研究。
T8761L [Leu15]-Gastrin I human acetate(39024-57-2 Free base)

[Leu15]-Gastrin I human acetate(39024-57-2 Free base) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T8761L。
T37960 Guanylin(human) TFA

Guanylin (human) TFA is a 15-amino acid peptide that serves as an endogenous activator of intestinal guanylate cyclase. This compound is primarily located in the gastrointestinal tract, where it regulates electrolyte and water transport in the intestinal and renal epithelia through a mechanism dependent on cyclic GMP. [1][2]
T38110 Galanin (Human) (Acetate)

Galanin (Human) (Acetate)是一种含有30个氨基酸的神经肽和丙氨酸(GAL)受体激动剂。在表达重组人gal1受体的HEK293E 细胞(EC50= 0.031 nM)中,它抑制佛司可林诱导的cAMP 产生,并刺激表达重组人gal2受体的CHO 细胞(EC50= 12.3 nM)中肌醇磷酸的积累。Galanin (Human) (Acetate)诱导离体大鼠纵向眼底收缩,ec50值为13.8 nM。在大鼠福尔马林试验的第二阶段,鞘内给药人甘丙肽(3、10和30 nmol/只)可减少大鼠舔爪和退缩。
T36926 Neuropeptide SF (human)

Neuropeptide SF (human) 显着增加异源表达 ASIC3 的持续电流幅度(FMRFamide 和 NPFF 分别为 12 倍和 19 倍和 9 倍),EC50 约为 50 μM。
T40550 Human β-defensin-1

Human β-defensin-1,HβD-1

Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by epithelial surfaces, circulatory cells, and cells of the reproductive tract. It exhibits antimicrobial activity against a wide range of sperm bacteria.
T36864 GRP (human) (trifluoroacetate salt)

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend...
T36446 Neuropeptide Y (human) (TFA)

Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
T39683 Human β-defensin-3

Human β-defensin-3,HβD-3

Human β-defensin-3 (HβD-3) is an antibiotic antimicrobial peptide synthesized by epithelial cells. It exhibits potent antimicrobial properties and mitigates inflammatory cytokine responses. HβD-3 efficiently targets various microorganisms, displaying IC90 values ranging from 6 to 25 μg/ml.

化合物

KY02111
Cat.No: T2052
Synonym:
Target: Wnt/beta-catenin
Des(benzylpyridyl) Atazanavi
Cat.No: T1883
Synonym:
Target: HIV Protease
Atazanavir
Cat.No: T0100L
Synonym: Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632
Target: P450, SARS-CoV, HIV Protease, P-gp
Atazanavir sulfate
Cat.No: T0100
Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦
Target: P450, SARS-CoV, HIV Protease, P-gp
GIP (human) acetate
Cat.No: TP2018L
Synonym: GIP (human) acetate(100040-31-1 Free base)
Target: IGF-1R
PEN (human) aceate
Cat.No: TP1949L
Synonym:
Target: GPCR19
Fibrinopeptide A, human acetate
Cat.No: TP1143L
Synonym: Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate
Target: Others
Hemopressin (human, mouse) acetate
Cat.No: TP1900L1
Synonym: Hemopressin (human, mouse) acetate(1314035-51-2 free base)
Target: Cannabinoid Receptor
Hemokinin 1 (human) acetate(491851-53-7 free base)
Cat.No: TP1899L1
Synonym:
Target: Neurokinin receptor
Neuropeptide SF (human) aceate
Cat.No: T36926L
Synonym:
Target: Others
Pancreatic Polypeptide (human) acetate
Cat.No: TP1137L
Synonym:
Target: Neuropeptide Y Receptor
RFRP3(human) acetate(311309-27-0 free base)
Cat.No: TP1936L1
Synonym:
Target: Neuropeptide Y Receptor
MOTS-c(Human) Acetate(1627580-64-6 free)
Cat.No: TP2312
Synonym:
Target: Others, AMPK
Mini Gastrin I, human acetate
Cat.No: TP1821L
Synonym:
Target: cholecystokinin
Enterostatin, human, mouse, rat acetate
Cat.No: TP1835L
Synonym:
Target: Endogenous Metabolite
LL-37, Human acetate(154947-66-7 free base)
Cat.No: TP1775L
Synonym:
Target: Antibacterial
ELA-11 (human) acetate(1784687-32-6 free base)
Cat.No: TP1922L1
Synonym:
Target: Apelin receptor, Arrestin
ELA-14(human) acetate
Cat.No: TP1923L1
Synonym: ELA-14(human) acetate (1886973-05-2 free base)
Target: Apelin receptor, Arrestin
C-Type Natriuretic Peptide (CNP) (1-22), human
Cat.No: TP1187
Synonym: CNP (1-22), human
Target: RAAS
Neuropeptide W-23(human)
Cat.No: TP1073
Synonym: NPW-23
Target: Others
Kisspeptin-10, human (TFA)(374675-21-5,FREE)
Cat.No: TP1345
Synonym:
Target: GPR, Kisspeptin
Endothelin 1 (swine, human) acetate
Cat.No: T19309L1
Synonym: Endothelin 1 (swine, human) acetate(117399-94-7 free base)
Target: Endothelin Receptor
RFRP-1 (human) acetate(311309-25-8 free base)
Cat.No: TP1937L1
Synonym:
Target: Neuropeptide Y Receptor
Cortistatin 14, human, rat acetate
Cat.No: TP1188L
Synonym:
Target: Somatostatin
Gastrin I (1-14), human
Cat.No: TP1705
Synonym:
Target: Others
β-Endorphin (1-27) (human) acetate
Cat.No: T38193L
Synonym: β-Endorphin (1-27) (human) acetate(76622-84-9 Free base)
Target: Opioid Receptor
BAD (103-127) (human) acetate
Cat.No: T40412L
Synonym: BAD (103-127) (human) acetate (331762-68-6 Free base)
Target: Others
Angiotensinogen (1-14), human acetate
Cat.No: TP1842L
Synonym:
Target: Endogenous Metabolite
PAMP-12 (human, porcine) acetate
Cat.No: TP1880L1
Synonym: PAMP-12 (human, porcine) acetate(196305-05-2 free base)
Target: Others
Glucagon (19-29), human acetate
Cat.No: TP1863L
Synonym:
Target: Glucagon Receptor
Corticotropin-releasing factor (human) acetate
Cat.No: TP1144L
Synonym: Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)
Target: CRFR
Apelin-17 (human, bovine) acetate
Cat.No: TP2092L
Synonym: Apelin-17 (human, bovine) acetate(217082-57-0 free base)
Target: HIV Protease
Tau protein (592-597), Human TFA
Cat.No: TP1453
Synonym:
Target: Others
TNF-α (31-45), human acetate
Cat.No: T19584L
Synonym: TNF-α (31-45), human acetate(144796-71-4 free base)
Target: Others
Adrenomedullin (AM) (22-52), human acetate
Cat.No: TP1257L
Synonym: Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base)
Target: CGRP Receptor
MART-1 (26-35) (human)
Cat.No: T7489
Synonym: MART-1 (26-35) human
Target: Others
Human growth hormone-releasing factor acetate
Cat.No: TP1155L
Synonym:
Target: GHSR
Peptide YY (PYY) (3-36), human
Cat.No: TP1059
Synonym: Peptide YY (3-36)
Target: Neuropeptide Y Receptor
Neuropeptide Y (29-64), amide, human acetate
Cat.No: TP1140L
Synonym:
Target: Neuropeptide Y Receptor
Human IgG4 (S228P) kappa, Isotype Control
Cat.No: T78339
Synonym:
Target: Others
VIP(6-28)(human, rat, porcine, bovine) acetate
Cat.No: TP1283L
Synonym:
Target: Others
PACAP-38 (31-38), human, mouse, rat acetate
Cat.No: TP1618L
Synonym: PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)
Target: PACAP
[Leu15]-Gastrin I human acetate(39024-57-2 Free base)
Cat.No: T8761L
Synonym:
Target:
Guanylin(human) TFA
Cat.No: T37960
Synonym:
Target:
Galanin (Human) (Acetate)
Cat.No: T38110
Synonym:
Target:
Neuropeptide SF (human)
Cat.No: T36926
Synonym:
Target:
Human β-defensin-1
Cat.No: T40550
Synonym: Human β-defensin-1,HβD-1
Target:
GRP (human) (trifluoroacetate salt)
Cat.No: T36864
Synonym:
Target:
Neuropeptide Y (human) (TFA)
Cat.No: T36446
Synonym:
Target:
Human β-defensin-3
Cat.No: T39683
Synonym: Human β-defensin-3,HβD-3
Target:
Cat. No. Product Name Target Signaling Pathways
TP2167 β-CGRP, human acetate

β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate

CGRP Receptor GPCR/G Protein; Neuroscience
β-CGRP, human acetate 是降钙素肽之一,通过受体活性修饰蛋白 (RAMP) 和降钙素受体样受体 (CRLR) 的复合物发挥作用(对于 CRLR/RAMP1 和 CRLR,IC50:1 nM 和 300 nM /RAMP2 在单元格中)。
T41030 γ-Globulins from human blood

Others Others
γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viral infections. These γ-globulins are specifically utilized in the treatment of common variable immunodeficiency.
T60104 Mycophenolic acid-β-D-glucuronide

Others Others
Mycophenolic acid glucuronide 是人血浆中mycophenolic acid 的葡糖甙代谢产物。
T1660 Silibinin

水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Silibinin (Silybin) 是水飞蓟的主要活性成分,具有抗癌和化疗预防作用,能抑制细胞增殖和迁移。
T0543 7-Methylxanthine

Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤

Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Adenosine Receptor Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
7-Methylxanthine 是一种黄嘌呤的甲基衍生物,是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。
T5269 N-Acetylornithine

Acetyl-ornithine,N-Acetyl-L-ornithine,N-乙酰鸟氨酸

Others; Endogenous Metabolite Metabolism; Others
N-Acetylornithine (N-Acetyl-L-ornithine) 是一种人内源性代谢物,是 L-谷氨酸到 L-精氨酸的酶促合成中的中间体。
T2S0265 Robinin

NSC 9222,刺槐素

TLR Immunology/Inflammation
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
TN6752 Dimethyl sulfone

Endogenous Metabolite Metabolism
Dimethyl sulfone 是内源性代谢产物的一种。
TN1933 Mitraphylline

帽柱木菲碱,帽柱叶碱

IL Receptor; TNF; NF-κB Apoptosis; Immunology/Inflammation; NF-κB
Mitraphylline 是一种绒毛钩藤中主要的五环吲哚类生物碱,可阻碍脂多糖介导的原代人中性粒细胞活化。
T4879 12-Hydroxydodecanoic acid

12-hydroxylauric acid,12-羟基月桂酸

Others; Endogenous Metabolite Metabolism; Others
12-Hydroxydodecanoic acid (12-hydroxylauric acid) 是内源性代谢产物的一种。
T11351 Galanthamine N-Oxide

AChE Neuroscience
Galanthamine N-Oxide 是分离于Zephyranthes concolor 的球茎中的一种生物碱。它抑制电鳗乙酰胆碱酯酶,EC50=26.2 μM。它是TcAChE,hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。
TN1305 Ethoxysanguinarine

乙氧基血根碱,6-Ethoxydihydrosanguinarine

Apoptosis; AChR Apoptosis; Neuroscience
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) 是存在于龙葵中的一种苯并菲啶生物碱天然产物,通过抑制蛋白磷酸酶 2A,可抑制结直肠癌细胞活力,诱导细胞凋亡。
TN4569 Minimolide F

Others Others
Minimolide F 是从 Centipeda minima 中分离得到的,对人鼻咽癌细胞具有抗增殖活性,IC50 为 17.4 μM。
T5573 Coenzyme Q9

辅酶Q9,Ubiquinone Q9,Ubiquinone 9,CoQ9

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Coenzyme Q9 (Ubiquinone 9) 是啮齿类动物泛醌的主要形式,是电子传递链中的一种双亲分子组分,具有内源性抗氧化剂的作用。它可减轻糖尿病引起的抗氧化防御机制的下降,改善左心室功能,减少心肌梗死面积和心肌细胞凋亡。
T3844 Deltonin

三角叶薯蓣皂苷

ERK; Others; Akt; Endogenous Metabolite Cytoskeletal Signaling; MAPK; Metabolism; Others; PI3K/Akt/mTOR signaling
Deltonin 是从盾叶薯蓣中得到的一种甾体皂苷,抑制ERK1/2和AKT 的活化,具有抗肿瘤活性。
T2S0357 6-Hydroxycoumarin

6-hydroxychromen-2-one,6-羟基香豆素

Others; Carbonic Anhydrase Metabolism; Others
6-Hydroxycoumarin (6-hydroxychromen-2-one) 是一种香豆素。其中香豆素具有抗炎,支气管扩张,解热,血管扩张,抗氧化,抗菌,抗真菌,抑菌和抗肿瘤作用。
T5750 Oxyberberine

氧化小檗碱,Ketoberberine,Berlambine,8-Oxoberberine

Others Others
Oxyberberine (8-Oxoberberine) 是天然的生物碱类物质。
T7458 5-Phenylvaleric Acid

Benzenepentanoic acid,5-苯基戊酸,Phenylvaleric Acid,Phenylpentanoic acid

Endogenous Metabolite Metabolism
5-Phenylvaleric Acid (Benzenepentanoic acid) 是细菌来源的戊酸,偶见于人体体液中。
T3768 Epifriedelanol

表木栓醇,Epifriedelinol

Others Others
Epifriedelanol (Epifriedelinol) 是一种分离自 Ulmus davidiana 根皮中的三萜类化合物,具有抗肿瘤作用,可以减缓人原始细胞的衰老。
T5120 Rhamnose

6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Calcium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。
T32291 Jineol

NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081

Others Others
Jineol (NSC-694081) 是一种来自蜈蚣 Scolopendra subspinipes 的喹啉生物碱。Jineol 在体外对人类肿瘤细胞系的生长具有细胞毒活性。
TN1520 Isoforskolin

Coleonol B

IL Receptor; TNF Apoptosis; Immunology/Inflammation
Isoforskolin 源自毛喉鞘蕊花,可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
TJP2872 Acevaltrate

Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate

ATPase; Others Membrane transporter/Ion channel; Others
Acevaltrate (Acevaltratum) 对人小细胞肺癌细胞系 GLC(4) 和人结肠直肠癌细胞系 COLO 320 具有高细胞毒性,IC50 值为 1-6 uM。它抑制大鼠肾和脑半球中 Na+/K+-ATP 酶活性,IC50分别为 22.8 和 42.3 μM。
T3O2784 Vitamin B6

维生素B6

Others Others
Vitamin B6 是人体某些辅酶的成分,参与多种代谢反应,特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。
T8103 H-HoArg-OH

Endogenous Metabolite; Phosphorylase Metabolism
H-HoArg-OH 是人骨和肝脏碱性磷酸酶(alkaline phosphatase)的强效抑制剂,是一种精氨酸的同系物。
T11218 ε-​Viniferin

epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体

P450 Metabolism
ε-​Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera,是 Resveratrol 的二聚体,能够抑制 CYP 家族,其 Ki=0.5~20 μM,具有抗氧化作用。
T5218 DL-Threitol

Others Others
DL-Threitol 是苏糖醇的 D-对映异构体。它具有作为人体代谢物的作用。它是 L-苏糖醇的对映异构体。
T4S1796 Heterophyllin B

PI3K PI3K/Akt/mTOR signaling
Heterophyllin B 是一种活性环肽,从 Pseudostellaria heterophylla 中分离得到,可用于研究食管癌。
T7970 7-Ethoxycoumarin

Others Others
7-Ethoxycoumarin 是细胞色素 P450(CYP) 的底物,现已被应用于多种 CYP 的功能表征。
T5223 Heneicosanoic acid

二十一碳酸,Heneicosylic Acid,C21:0

Others; Endogenous Metabolite Metabolism; Others
Heneicosanoic acid (C21:0) 是广泛存在于动植物中的长链饱和脂肪酸。
T2S2150 Noricaritin

诺里卡汀,去甲淫羊藿黄素

Others Others
Noricaritin 是一种来源于淫羊藿根的黄酮类化合物,可诱导肺组织细胞增殖,抑制人肺上皮细胞中促炎细胞因子和趋化因子的产生。
T4A2458 Resibufogenin

酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基,蟾力苏

Others Others
Resibufogenin (Bufogenin) 是华蟾素的成分之一,表现出抑制氧化应激及肿瘤再生的活性。
T3899 Calceolarioside B

Desrhamnosyl isoacteoside,木通苯乙醇苷 B,Nuomioside A,木通苯乙醇苷B

Aromatase Endocrinology/Hormones
Calceolarioside B (Desrhamnosyl isoacteoside) 是一种分离自Stauntonia hexaphylla 叶片中的天然产物。它抑制 DPPH 自由基清除活性(IC50:94.60 μM)。它显著抑制大鼠晶状体醛糖还原酶(RLAR)活性(C50:23.99 μM。
TN1110 Shanziside

山栀苷,Shanzhiside

IL Receptor Immunology/Inflammation
Shanziside (Shanzhiside) 是一种分离自福洛美属植物中的环烯醚萜苷类化合物。
T9605 Sangivamycin

BA-90912,桑霉素,NSC 65346

Nucleoside Antimetabolite/Analog; PKC Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T7224 Anabasine

(+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine

AChR Neuroscience
Anabasine ((S)-Anabasine) 是一种从烟草中提取的生物碱。Anabasine 是一种烟碱乙酰胆碱受体的全激动剂 (nAChRs),具有杀虫活性。Anabasine 促使内源表达人肌型 nAChRs 的 TE671 细胞去极化。
TN1094 Ginsenoside Rg6

人参皂苷Rg6,人参皂苷 Rg6

Apoptosis; NF-κB Apoptosis; NF-κB
Ginsenoside Rg6 抑制人淋巴瘤 JK 细胞增殖并诱导其凋亡,在 HepG2 细胞中抑制 TNF-α 诱导的 NF-κB 转录活性,IC50为 29.34 μM。
T6S1676 Cimigenoside

Others; Gamma-secretase Neuroscience; Others; Proteases/Proteasome; Stem Cells
Cimigenoside 是升麻属中的一种成分,是一种 γ-分泌酶抑制剂,通过 γ-分泌酶/Notch 轴抑制人类乳腺癌细胞的增殖或转移。
T4844 L-Methionine

L(-)-Methionin,L-蛋氨酸,L-Methionin

Endogenous Metabolite Metabolism
L-Methionine (L-Methionin) 是 Methionine 的 L-异构体。Methionine 是必需氨基酸,同时也是肝脏保护剂。
T3344 Ciwujianoside B

yemuoside YM,刺五加皂苷 B,acanthopanax senticosides B,刺五加皂甙 B,Ciwujianoside-B

BCL; Others Apoptosis; Others
Ciwujianoside B (acanthopanax senticosides B) 是刺五加的主要成分,能缓解疲劳,增强记忆力,提高人的认知能力。
T3S0012 coniferyl ferulate

P-gp; GST Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
Coniferyl ferulate 是从川芎中提取的一种天然产物,是强效的谷胱甘肽 S-转移酶抑制剂,强抑制人胎盘型谷胱甘肽 S-转移酶,IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
TN1393 (-)-Anonaine

番荔枝碱

Apoptosis; Antioxidant; Parasite; Antifungal Apoptosis; Microbiology/Virology; oxidation-reduction
(-)-Anonaine 可从木兰科和安妮科的几个物种中提取出来,具有抗疟、抗菌、抗真菌、抗氧化、抗癌、抗抑郁和血管舒张的活性。(-)-Anonaine 通过 Bax 和 caspase 依赖性途径诱导人类宫颈癌(HeLa)细胞的凋亡,诱导 DNA 损伤并抑制人类肺癌 h1299细胞的生长和迁移。
TL0006 Cichoric Acid

菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物,具有抗氧化作用。
T2S1086 Nepitrin

假荆芥属苷,Nepetin-7-glucoside

Antioxidant oxidation-reduction
Nepitrin (Nepetin-7-glucoside) 分离自Scrophularia striata 中,具有强大的抗炎、抗关节炎作用。
T35673 Stictic Acid

Scopularic acid

Others Others
Stictic Acid (Scopularic acid) 分离自苏门答腊地衣 Stereocaulon montagneanum,可抑制 HT-29 人结肠腺癌细胞的生长,IC50 为 29.29 μg/ml。
T1709 2'-Deoxyinosine

Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxyinosine (Guanine deoxyriboside) 具有 抑制人癌细胞株生长的活性,并发现其与嘌呤核苷磷酸化酶缺乏有关。
T4812 D-Mannose

D-(+)-Mannose,D-甘露糖

Endogenous Metabolite Metabolism
D-Mannose (D-(+)-Mannose) 是糖类,在人体代谢过程,尤其在特定蛋白的糖基化过程中具有重要作用。
T34398 Rotundifuran

Others Others
Rotundifuran 是从 Vitex rotundifolia 的果实中提取的。 Rotundifuran 抑制细胞周期进程并诱导人髓性白血病细胞凋亡。
TN4618 N-trans-Sinapoyltyramine

Others Others
N-trans-Sinapoyltyramine 对 HeLa 人癌细胞系表现出强烈的选择性细胞毒性,IC50 值为 9.77 ± 1.25 μm。
TMS0484 Episyringaresinol 4'-O-β-D-glncopyranoside

(-)-丁香树脂酚-4-O-β-D-葡萄糖苷,(-)-Syringaresinol 4-O-β-D-glucopyranosi

Others Others
Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) 是一种天然的潜在神经炎症抑制剂,分离自鼠尾草 (Alhagi sparsifoliaShap) 。
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天然产物

β-CGRP, human acetate
Cat.No: TP2167
Synonym: β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate
Target: CGRP Receptor
γ-Globulins from human blood
Cat.No: T41030
Synonym:
Target: Others
Mycophenolic acid-β-D-glucuronide
Cat.No: T60104
Synonym:
Target: Others
Silibinin
Cat.No: T1660
Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I
Target: Reactive Oxygen Species, Autophagy
7-Methylxanthine
Cat.No: T0543
Synonym: Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤
Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Adenosine Receptor
N-Acetylornithine
Cat.No: T5269
Synonym: Acetyl-ornithine,N-Acetyl-L-ornithine,N-乙酰鸟氨酸
Target: Others, Endogenous Metabolite
Robinin
Cat.No: T2S0265
Synonym: NSC 9222,刺槐素
Target: TLR
Dimethyl sulfone
Cat.No: TN6752
Synonym:
Target: Endogenous Metabolite
Mitraphylline
Cat.No: TN1933
Synonym: 帽柱木菲碱,帽柱叶碱
Target: IL Receptor, TNF, NF-κB
12-Hydroxydodecanoic acid
Cat.No: T4879
Synonym: 12-hydroxylauric acid,12-羟基月桂酸
Target: Others, Endogenous Metabolite
Galanthamine N-Oxide
Cat.No: T11351
Synonym:
Target: AChE
Ethoxysanguinarine
Cat.No: TN1305
Synonym: 乙氧基血根碱,6-Ethoxydihydrosanguinarine
Target: Apoptosis, AChR
Minimolide F
Cat.No: TN4569
Synonym:
Target: Others
Coenzyme Q9
Cat.No: T5573
Synonym: 辅酶Q9,Ubiquinone Q9,Ubiquinone 9,CoQ9
Target: Apoptosis, Endogenous Metabolite
Deltonin
Cat.No: T3844
Synonym: 三角叶薯蓣皂苷
Target: ERK, Others, Akt, Endogenous Metabolite
6-Hydroxycoumarin
Cat.No: T2S0357
Synonym: 6-hydroxychromen-2-one,6-羟基香豆素
Target: Others, Carbonic Anhydrase
Oxyberberine
Cat.No: T5750
Synonym: 氧化小檗碱,Ketoberberine,Berlambine,8-Oxoberberine
Target: Others
5-Phenylvaleric Acid
Cat.No: T7458
Synonym: Benzenepentanoic acid,5-苯基戊酸,Phenylvaleric Acid,Phenylpentanoic acid
Target: Endogenous Metabolite
Epifriedelanol
Cat.No: T3768
Synonym: 表木栓醇,Epifriedelinol
Target: Others
Rhamnose
Cat.No: T5120
Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose
Target: Calcium Channel, Endogenous Metabolite
Jineol
Cat.No: T32291
Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081
Target: Others
Isoforskolin
Cat.No: TN1520
Synonym: Coleonol B
Target: IL Receptor, TNF
Acevaltrate
Cat.No: TJP2872
Synonym: Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate
Target: ATPase, Others
Vitamin B6
Cat.No: T3O2784
Synonym: 维生素B6
Target: Others
H-HoArg-OH
Cat.No: T8103
Synonym:
Target: Endogenous Metabolite, Phosphorylase
ε-​Viniferin
Cat.No: T11218
Synonym: epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体
Target: P450
DL-Threitol
Cat.No: T5218
Synonym:
Target: Others
Heterophyllin B
Cat.No: T4S1796
Synonym:
Target: PI3K
7-Ethoxycoumarin
Cat.No: T7970
Synonym:
Target: Others
Heneicosanoic acid
Cat.No: T5223
Synonym: 二十一碳酸,Heneicosylic Acid,C21:0
Target: Others, Endogenous Metabolite
Noricaritin
Cat.No: T2S2150
Synonym: 诺里卡汀,去甲淫羊藿黄素
Target: Others
Resibufogenin
Cat.No: T4A2458
Synonym: 酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基,蟾力苏
Target: Others
Calceolarioside B
Cat.No: T3899
Synonym: Desrhamnosyl isoacteoside,木通苯乙醇苷 B,Nuomioside A,木通苯乙醇苷B
Target: Aromatase
Shanziside
Cat.No: TN1110
Synonym: 山栀苷,Shanzhiside
Target: IL Receptor
Sangivamycin
Cat.No: T9605
Synonym: BA-90912,桑霉素,NSC 65346
Target: Nucleoside Antimetabolite/Analog, PKC
Anabasine
Cat.No: T7224
Synonym: (+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine
Target: AChR
Ginsenoside Rg6
Cat.No: TN1094
Synonym: 人参皂苷Rg6,人参皂苷 Rg6
Target: Apoptosis, NF-κB
Cimigenoside
Cat.No: T6S1676
Synonym:
Target: Others, Gamma-secretase
L-Methionine
Cat.No: T4844
Synonym: L(-)-Methionin,L-蛋氨酸,L-Methionin
Target: Endogenous Metabolite
Ciwujianoside B
Cat.No: T3344
Synonym: yemuoside YM,刺五加皂苷 B,acanthopanax senticosides B,刺五加皂甙 B,Ciwujianoside-B
Target: BCL, Others
coniferyl ferulate
Cat.No: T3S0012
Synonym:
Target: P-gp, GST
(-)-Anonaine
Cat.No: TN1393
Synonym: 番荔枝碱
Target: Apoptosis, Antioxidant, Parasite, Antifungal
Cichoric Acid
Cat.No: TL0006
Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
Nepitrin
Cat.No: T2S1086
Synonym: 假荆芥属苷,Nepetin-7-glucoside
Target: Antioxidant
Stictic Acid
Cat.No: T35673
Synonym: Scopularic acid
Target: Others
2'-Deoxyinosine
Cat.No: T1709
Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷
Target: Others, Endogenous Metabolite
D-Mannose
Cat.No: T4812
Synonym: D-(+)-Mannose,D-甘露糖
Target: Endogenous Metabolite
Rotundifuran
Cat.No: T34398
Synonym:
Target: Others
N-trans-Sinapoyltyramine
Cat.No: TN4618
Synonym:
Target: Others
Episyringaresinol 4'-O-β-D-glncopyranoside
Cat.No: TMS0484
Synonym: (-)-丁香树脂酚-4-O-β-D-葡萄糖苷,(-)-Syringaresinol 4-O-β-D-glucopyranosi
Target: Others
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Cat. No. Product Name Species Expression System
TMPU-00004 STAT5A Protein, Human, Recombinant (His)

MGF,Signal transducer and activator of transcriptio...

Human E. coli
Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de...
TMPU-00002 SOS1-Cat Protein, Human, Recombinant (His)

SOS-1,Son of sevenless homolog 1

Human E. coli
Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM:610733]. NS4 is an autosomal dominant disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. It is a genetically heterogeneous and relatively common syndrome, with an estimated incid...
TMPY-06318 Alpha-Synuclein Protein,Human,Recombinant (H50Q)

Human α-Synuclein Protein (H50Q),synuclein, alpha (...

Human E. coli
Alpha-Synuclein Protein,Human,Recombinant (H50Q) is expressed in E. coli expression system. The predicted molecular weight is 14.45 kDa and the accession number is P37840-1.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPY-03484 TCPTP Protein, Human, Recombinant

TCPTP,protein tyrosine phosphatase, non-receptor type 2,PTPT...

Human Baculovirus Insect Cells
TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPY-02327 HGF Protein, Human, Recombinant

SF,hepatocyte growth factor (hepapoietin A,HGFB,F-TCF,F-TCFB...

Human CHO Cells
HGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 79.7 kDa and the accession number is P14210-1.
TMPY-00749 FGF-2 Protein, Human, Recombinant

fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF

Human E. coli
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPY-01560 EGF Protein, Human, Recombinant

URG,epidermal growth factor,表皮生长因子,HOMG4

Human E. coli
EGF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.35 kDa and the accession number is P01133-1.
TMPY-02881 RAGE Protein, Human, Recombinant

RAGE,advanced glycosylation end product-specific receptor

Human HEK293 Cells
RAGE Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35 kDa and the accession number is A0A1U9X785.
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04330 Mer Protein, Human, Recombinant

MER proto-oncogene, tyrosine kinase,RP38,MER,c-mer,Tyro12,c-...

Human HEK293 Cells
Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.
TMPY-04104 LIF Protein, Human, Recombinant

CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA

Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-01010 NGF Protein, Human, Recombinant

Beta-NGF,神经生长因子,β-NGF,NGFB,nerve growth factor (β polypeptid...

Human CHO Cells
NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138.
TMPJ-01430 NovoNectin Protein, Human, Recombinant

NovoNectin,Cold-insoluble globulin,FN,CIG,Fibronectin,Fibron...

Human E. coli
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a hepar...
TMPY-00875 Leptin Protein, Human, Recombinant

OBS,leptin,OB,LEPD

Human E. coli
Leptin Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A4D0Y8.
TMPY-00395 Insulin Protein, Human, Recombinant

IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS

Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ...
TMPY-03782 Albumin Protein, Human, Recombinant

PRO0883,albumin,FDAH,PRO0903,PRO1341,ANALBA

Human P. pastoris (Yeast)
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-05176 AMH Protein, Human, Recombinant (His)

MIS,anti-Mullerian hormone,MIF

Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPY-00871 LAYN Protein, Human, Recombinant (hFc)

layilin

Human HEK293 Cells
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-00989 LDLR Protein, Human, Recombinant (His)

low density lipoprotein receptor,FHC,FH,LDLCQ2,LDL Receptor,...

Human HEK293 Cells
LDLR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is A0A024R7D5.
TMPY-01756 Transthyretin Protein, Human, Recombinant (His)

PALB,HEL111,CTS,transthyretin,CTS1,HsT2651,TBPA

Human HEK293 Cells
Transthyretin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is E9KL36.
TMPY-03958 TGF alpha Protein, Human, Recombinant

transforming growth factor α,转化生长因子,transforming growth fact...

Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-00856 TCCR Protein, Human, Recombinant (hFc)

WSX1,interleukin 27 receptor, α,IL27R,TCCR,IL-27RA,interleuk...

Human HEK293 Cells
TCCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q6UWB1.
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-01864 CNTF Protein, Human, Recombinant (His)

ciliary neurotrophic factor,HCNTF

Human E. coli
CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441.
TMPY-01030 TFPI Protein, Human, Recombinant (His)

TFPI1,tissue factor pathway inhibitor (lipoprotein-associate...

Human HEK293 Cells
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPY-01714 IFN gamma Protein, Human, Recombinant

IFI,interferon, γ,IFN γ,IFG,IFN gamma,interferon, gamma,干扰素,...

Human CHO Cells
IFN gamma Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 16.7 kDa and the accession number is A0A7R8GUN6.
TMPY-04329 Vimentin Protein, Human, Recombinant (His)

CTRCT30,HEL113,vimentin

Human Baculovirus Insect Cells
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ...
TMPY-01085 VLDLR Protein, Human, Recombinant (His)

VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...

Human HEK293 Cells
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ...
TMPY-01008 VEGFD Protein, Human, Recombinant (His)

VEGFD,c-fos induced growth factor (vascular endothelial grow...

Human HEK293 Cells
VEGFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is O43915.
TMPY-00392 PAM Protein, Human, Recombinant (His)

PAL,peptidylglycine alpha-amidating monooxygenase,peptidylgl...

Human HEK293 Cells
PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2.
TMPY-01009 TGFBI Protein, Human, Recombinant (His)

CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...

Human HEK293 Cells
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPY-02848 Adiponectin Protein, Human, Recombinant (hFc)

ADPN,adiponectin, C1Q and collagen domain containing,APM-1,A...

Human HEK293 Cells
Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848.
TMPY-02801 PHGDH Protein, Human, Recombinant (His)

phosphoglycerate dehydrogenase,HEL-S-113,3PGDH,NLS1,PHGDHD,P...

Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PH...
TMPK-00369 HGF Protein, Human, Recombinant (hFc)

HGF,F-TCF,HGFB,SF,F-TCFB,肝细胞生长因子,DFNB39,Hepatopoietin-A,HPTA

Human HEK293 Cells
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pa...
TMPJ-00235 TPO Protein, Human, Recombinant (His)

Megakaryocyte growth and development factor,C-mpl ligand,Thr...

Human HEK293 Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi...
TMPY-02543 PCNA Protein, Human, Recombinant (His)

ATLD2,proliferating cell nuclear antigen

Human Baculovirus Insect Cells
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPY-05202 Noggin/NOG Protein, Human, Recombinant

noggin,SYNS1,SYM1

Human HEK293 Cells
Noggin/NOG Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.1 kDa and the accession number is Q13253.
TMPY-02204 LBP Protein, Human, Recombinant (His)

BPIFD2,lipopolysaccharide binding protein

Human HEK293 Cells
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end...
TMPY-04778 Prolactin Protein, Human, Recombinant (His)

prolactin

Human Baculovirus Insect Cells
Prolactin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is P01236.
TMPY-02927 RAGE Protein, Human, Recombinant (His)

RAGE,advanced glycosylation end product-specific receptor

Human HEK293 Cells
RAGE Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is A0A1U9X785.
TMPY-05357 GCDH Protein, Human, Recombinant (His)

ACAD5,glutaryl-CoA dehydrogenase,GCD

Human Baculovirus Insect Cells
GCDH Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is Q92947-1.
TMPY-05462 Albumin Protein, Human, Recombinant, Biotinylated

PRO0883,PRO1341,ANALBA,PRO0903,FDAH,albumin

Human P. pastoris (Yeast)
Albumin Protein, Human, Recombinant, Biotinylated is expressed in yeast. The predicted molecular weight is 66.5 kDa and the accession number is P02768-1.
TMPY-01413 Cripto Protein, Human, Recombinant (His)

CR,CRIPTO,teratocarcinoma-derived growth factor 1,CRGF

Human HEK293 Cells
Cripto Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is AAH22393.1.
TMPY-00742 EGFR Protein, Human, Recombinant (His)

mENA,NISBD2,ERBB1,HER1,PIG61,ERBB,epidermal growth factor re...

Human HEK293 Cells
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-03532 LIF Protein, Human, Recombinant (His)

Leukemia Inhibitory Factor,HILDA,DIA,白血病抑制因子,MLPLI,CDF

Human HEK293 Cells
LIF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.2 kDa and the accession number is P15018.
TMPY-01601 AXL Protein, Human, Recombinant (His)

UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7

Human HEK293 Cells
AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
TMPY-02846 CLPS Protein, Human, Recombinant (His)

colipase, pancreatic

Human Baculovirus Insect Cells
CLPS Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.5 kDa and the accession number is P04118.
TMPY-01188 PARP Protein, Human, Recombinant (His)

ADPRT1,ADPRT,pADPRT-1,PPOL,ARTD1,PARP-1,poly (ADP-ribose) po...

Human Baculovirus Insect Cells
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8.
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重组蛋白

STAT5A Protein, Human, Recombinant (His)
Cat.No: TMPU-00004
Species: Human
Expression System: E. coli
SOS1-Cat Protein, Human, Recombinant (His)
Cat.No: TMPU-00002
Species: Human
Expression System: E. coli
Alpha-Synuclein Protein,Human,Recombinant (H50Q)
Cat.No: TMPY-06318
Species: Human
Expression System: E. coli
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
TCPTP Protein, Human, Recombinant
Cat.No: TMPY-03484
Species: Human
Expression System: Baculovirus Insect Cells
HGF Protein, Human, Recombinant
Cat.No: TMPY-02327
Species: Human
Expression System: CHO Cells
FGF-2 Protein, Human, Recombinant
Cat.No: TMPY-00749
Species: Human
Expression System: E. coli
EGF Protein, Human, Recombinant
Cat.No: TMPY-01560
Species: Human
Expression System: E. coli
RAGE Protein, Human, Recombinant
Cat.No: TMPY-02881
Species: Human
Expression System: HEK293 Cells
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
Mer Protein, Human, Recombinant
Cat.No: TMPY-04330
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
Cat.No: TMPY-04104
Species: Human
Expression System: HEK293 Cells
NGF Protein, Human, Recombinant
Cat.No: TMPY-01010
Species: Human
Expression System: CHO Cells
NovoNectin Protein, Human, Recombinant
Cat.No: TMPJ-01430
Species: Human
Expression System: E. coli
Leptin Protein, Human, Recombinant
Cat.No: TMPY-00875
Species: Human
Expression System: E. coli
Insulin Protein, Human, Recombinant
Cat.No: TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
Albumin Protein, Human, Recombinant
Cat.No: TMPY-03782
Species: Human
Expression System: P. pastoris (Yeast)
AMH Protein, Human, Recombinant (His)
Cat.No: TMPY-05176
Species: Human
Expression System: HEK293 Cells
LAYN Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00871
Species: Human
Expression System: HEK293 Cells
LDLR Protein, Human, Recombinant (His)
Cat.No: TMPY-00989
Species: Human
Expression System: HEK293 Cells
Transthyretin Protein, Human, Recombinant (His)
Cat.No: TMPY-01756
Species: Human
Expression System: HEK293 Cells
TGF alpha Protein, Human, Recombinant
Cat.No: TMPY-03958
Species: Human
Expression System: E. coli
TCCR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00856
Species: Human
Expression System: HEK293 Cells
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
CNTF Protein, Human, Recombinant (His)
Cat.No: TMPY-01864
Species: Human
Expression System: E. coli
TFPI Protein, Human, Recombinant (His)
Cat.No: TMPY-01030
Species: Human
Expression System: HEK293 Cells
IFN gamma Protein, Human, Recombinant
Cat.No: TMPY-01714
Species: Human
Expression System: CHO Cells
Vimentin Protein, Human, Recombinant (His)
Cat.No: TMPY-04329
Species: Human
Expression System: Baculovirus Insect Cells
VLDLR Protein, Human, Recombinant (His)
Cat.No: TMPY-01085
Species: Human
Expression System: HEK293 Cells
VEGFD Protein, Human, Recombinant (His)
Cat.No: TMPY-01008
Species: Human
Expression System: HEK293 Cells
PAM Protein, Human, Recombinant (His)
Cat.No: TMPY-00392
Species: Human
Expression System: HEK293 Cells
TGFBI Protein, Human, Recombinant (His)
Cat.No: TMPY-01009
Species: Human
Expression System: HEK293 Cells
Adiponectin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02848
Species: Human
Expression System: HEK293 Cells
PHGDH Protein, Human, Recombinant (His)
Cat.No: TMPY-02801
Species: Human
Expression System: E. coli
HGF Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00369
Species: Human
Expression System: HEK293 Cells
TPO Protein, Human, Recombinant (His)
Cat.No: TMPJ-00235
Species: Human
Expression System: HEK293 Cells
PCNA Protein, Human, Recombinant (His)
Cat.No: TMPY-02543
Species: Human
Expression System: Baculovirus Insect Cells
Noggin/NOG Protein, Human, Recombinant
Cat.No: TMPY-05202
Species: Human
Expression System: HEK293 Cells
LBP Protein, Human, Recombinant (His)
Cat.No: TMPY-02204
Species: Human
Expression System: HEK293 Cells
Prolactin Protein, Human, Recombinant (His)
Cat.No: TMPY-04778
Species: Human
Expression System: Baculovirus Insect Cells
RAGE Protein, Human, Recombinant (His)
Cat.No: TMPY-02927
Species: Human
Expression System: HEK293 Cells
GCDH Protein, Human, Recombinant (His)
Cat.No: TMPY-05357
Species: Human
Expression System: Baculovirus Insect Cells
Albumin Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05462
Species: Human
Expression System: P. pastoris (Yeast)
Cripto Protein, Human, Recombinant (His)
Cat.No: TMPY-01413
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His)
Cat.No: TMPY-00742
Species: Human
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant (His)
Cat.No: TMPY-03532
Species: Human
Expression System: HEK293 Cells
AXL Protein, Human, Recombinant (His)
Cat.No: TMPY-01601
Species: Human
Expression System: HEK293 Cells
CLPS Protein, Human, Recombinant (His)
Cat.No: TMPY-02846
Species: Human
Expression System: Baculovirus Insect Cells
PARP Protein, Human, Recombinant (His)
Cat.No: TMPY-01188
Species: Human
Expression System: Baculovirus Insect Cells
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Cat. No. Product Name Target Signaling Pathways
TMIH-0521 Silibinin-d3

Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分,具有抗癌和化疗预防作用,能抑制细胞增殖和迁移。
T12638 (R)-Praziquantel-d11

(R)-吡喹酮 D11,(R)-Praziquantel D11

5-HT Receptor GPCR/G Protein; Neuroscience
(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist
T13291 VD3-D6

Vitamin D3-26,26,26,27,27,27-d6

Others Others
VD3-D6 is the deuterated form of Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.
T71300 Pentoxifylline-d6

Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/...
T11655 Indomethacin-D4

Indometacin-D4,吲哚美辛-D4

CDK Cell Cycle/Checkpoint
Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.
T19489 O-Desmethyl gefitinib D8

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
O-Desmethyl gefitinib D8 is a deuterium labeled O-Desmethyl gefitinib that is an active metabolite of Gefitinib in human plasma.
T12487 Piroxicam D3

吡罗昔康 D3,CP-16171 D3

Others Others
Piroxicam D3 is deuterium labeled Piroxicam. Piroxicam is a COX inhibitor(human monocyte COX-1 and COX-2 with IC50s of 47, 25 μM , respectively) .
T11229 Erlotinib-d6

OSI-774 D6,NSC 718781 D6,CP-358774 D6

Others Others
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
T10349 Apixaban 13C,d3

Apixaban 13CD3,BMS-562247-01 13CD3

Others Others
Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit).
T11276 Fexofenadine-d6

MDL-16455-d6,Terfenadine carboxylate-d6

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Fexofenadine-d6 (MDL-16455-d6) 是 Fexofenadine 的氘代物,可用做检测人血浆中非索非那定浓度的内标。
T10610 Brexpiprazole-d8

OPC-34712 D8

Others Others
Brexpiprazole D8 (OPC-34712 D8) is a deuterium-labeled Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Ki: 0.12 nM and 0.3 nM).
T11995 Melatonin-d4

N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5

Others Others
Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.
T10611 Brexpiprazole S-oxide D8

DM-3411 D8

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Kis: 0.12 nM and 0.3 nM).
T35695 Oleic Acid-13C

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximate...
T35915 Erlotinib-13C6

Erlotinib-13C6

Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
TMIH-0359 Mycophenolic Acid-d3 Phenyl Glucuronide

Mycophenolic Acid-d3 Phenyl Glucuronide 是 Mycophenolic Acid Phenyl Glucuronide 的氘代化合物。Mycophenolic Acid Phenyl Glucuronide 的 CAS 号为 31528-44-6。Mycophenolic acid glucuronide是人血浆中mycophenolic acid的葡糖甙代谢产物。
T71893 Clobetasol Propionate-d5

Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 µg/ml. Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the t...
T11246 Etoricoxib-d4

MK-0663 D4,依托考昔 D4,L-791456 D4,Etoricoxib D4

Others Others
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
TMIJ-0451 Malathion-d10

Malathion-d10 是 Malathion 的氘代化合物。Malathion 的 CAS 号为 121-75-5。Malathion 是一种杀虫剂,是一种有机磷酸酯的副交感神经药物,不可逆地与胆碱酯酶结合,具有相对较低的人体毒性。
TMIJ-0434 p-Benzoquinone-d4

p-Benzoquinone-d4 是 p-Benzoquinone 的氘代化合物。p-Benzoquinone 的 CAS 号为 106-51-4。p-Benzoquinone 是一种超氧化物清除剂。它是一种在人体血液中发现的有毒代谢物。
TMIJ-0456 Malathion-d7

Malathion-d7 是 Malathion 的氘代化合物。Malathion 的 CAS 号为 121-75-5。Malathion 是一种杀虫剂,是一种有机磷酸酯的副交感神经药物,不可逆地与胆碱酯酶结合,具有相对较低的人体毒性。
TMID-0010 Mavacamten-d6

Mavacamten-d6 是 Mavacamten 的氘代化合物。Mavacamten 的 CAS 号为 1642288-47-8。MYK-461 是一种可口服的心肌肌球蛋白 ATP 酶抑制剂,在牛心脏和人心脏中的IC50值分别为 490和711 nM。
TMIJ-0108 rac-Hesperetin-13C-d3

rac-Diosmin EP Impurity G-13C-d3

rac-Hesperetin-13C-d3 是 rac-Hesperetin 的 13C 和氘代化合物。rac-Hesperetin 的 CAS 号为 69097-99-0。
T73711 Atomoxetine-d3 hydrochloride

Atomoxetine-d3 hydrochloride 是氘代标记的Atomoxetine hydrochloride。Atomoxetine hydrochloride 是去甲肾上腺素重吸收抑制剂,与人NET,SERT 和DAT 的放射性配体结合的 Ki 分别为5,77和1451 nM。
TMIH-0198 DM-3411-d8

Brexpiprazole Metabolite

DM-3411-d8 是 DM-3411 的氘代化合物。DM-3411 的 CAS 号为 913611-97-9。Brexpiprazole是人5-HT1A和多巴胺受体的部分激动剂,Ki分别为0.12 和 0.3 nM。它也是5-HT2A受体的拮抗剂,Ki为 0.47 nM,可作为非典型抗精神病药。
T71326 1,3,7-Trimethyluric Acid-d9

1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.
T71302 Norfluoxetine-d5 HCl

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T71286 Guaifenesin-d3

Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing ...
T71145 Racecadotril-d5

Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan. In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively. It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-indu...
TMIJ-0215 Doxofylline-d4

Doxofylline-d4 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂,且能抑制磷酸二酯酶 IV,用于治疗哮喘。
TMID-0118 Doxofylline-d6

Doxofylline-d6 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂,且能抑制磷酸二酯酶 IV,用于治疗哮喘。
T71211 Rizatriptan-d6 benzoate salt

Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors. Rizatriptan induces vasoconstriction in isolated human middle meningeal arteries. In vivo, rizatriptan reduces head grooming, the number of oculotemporal strokes, eye blinking, and one-eye closures in a Cacna1a mutant transgenic mou...
T71303 Flufenamic Acid-d4

Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...
TMIH-0209 Elobixibat-d5

Elobixibat-d5 是 Elobixibat 的氘代化合物。Elobixibat 的 CAS 号为 439087-18-0。Elobixibat 是回肠胆汁酸转运蛋白的抑制剂(小鼠、人和犬 IBAT 的 IC50:0.13 nM、0.53 nM 和 5.8 nM)。 Elobixibat 可用于慢性特发性便秘的研究。
T73820 Bosentan-d4

Bosentan-d4 是 Bosentan 的氘代物。Bosentan 是一种有效的endothelin-1 (ET)拮抗剂,在人的 SMC 细胞中,作用于ETA 和ETB 受体,Ki 值分别为 4.7 nM 和 95 nM。
T38356 1,2-Dipalmitoyl-13C-sn-glycero-3-PC

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...
TMIJ-0332 Taurolithocholic Acid-d5 Sodium Salt (Major)

Taurolithocholic Acid-d5 Sodium Salt (Major) 是 Taurolithocholic Acid Sodium Salt 的氘代化合物。Taurolithocholic Acid Sodium Salt 的 CAS 号为 6042-32-6。Taurolithocholic acid sodium salt 是抑胆剂和Ca2+激动剂,可抑制放射性配体与毒蕈碱 M1 结合。
T69758 Flutamide-d7

Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
TMIH-0368 Naringenin-d4

Naringenin-d4 是 Naringenin 的氘代化合物。Naringenin 的 CAS 号为 480-41-1。Naringenin是葡萄柚中主要的黄烷酮,可作为抗氧化剂、自由基清除剂、抗炎剂、碳水化合物代谢促进剂、免疫系统调节剂。
TMIJ-0470 Folpet-d4

Folpet-d4 是 Folpet 的氘代化合物。Folpet 的 CAS 号为 133-07-3。Folpet 是一种广泛使用的二甲酰亚胺类杀菌剂,可诱发小鼠胃肠道肿瘤,主要发生在十二指肠,对人支气管上皮细胞也有细胞毒作用。
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T71143 Ambroxol-d5

Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part...
T35783 Zearalenone-13C18

Zearalenone-13C18

Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also i...
T36059 Dichlorphenamide-13C6

Dichlorphenamide-13C6

Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively).1It lowers intraocular pressure in rabbits when 50 μl of a 10% solution is applied topically to the eye.2Dichlorphenamide rescues the potassium deficiency and prevents insulin-induc...
TMIJ-0519 Fosaprepitant-d4 Dimeglumine

Fosaprepitant-d4 Dimeglumine 是 Fosaprepitant Dimeglumine 的氘代化合物。Fosaprepitant Dimeglumine 的 CAS 号为 265121-04-8。Fosaprepitant dimeglumine 是 Aprepitant 的前药。它是一种神经激肽 1 受体拮抗剂,可用于预防化疗引起的恶心呕吐。
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T69395 Nicotinamide-d4

Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl...
T71212 Lornoxicam-d4

Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
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同位素标记化合物

Silibinin-d3
Cat.No: TMIH-0521
Synonym:
Target:
(R)-Praziquantel-d11
Cat.No: T12638
Synonym: (R)-吡喹酮 D11,(R)-Praziquantel D11
Target: 5-HT Receptor
VD3-D6
Cat.No: T13291
Synonym: Vitamin D3-26,26,26,27,27,27-d6
Target: Others
Pentoxifylline-d6
Cat.No: T71300
Synonym:
Target:
Indomethacin-D4
Cat.No: T11655
Synonym: Indometacin-D4,吲哚美辛-D4
Target: CDK
O-Desmethyl gefitinib D8
Cat.No: T19489
Synonym:
Target: EGFR
Piroxicam D3
Cat.No: T12487
Synonym: 吡罗昔康 D3,CP-16171 D3
Target: Others
Erlotinib-d6
Cat.No: T11229
Synonym: OSI-774 D6,NSC 718781 D6,CP-358774 D6
Target: Others
Apixaban 13C,d3
Cat.No: T10349
Synonym: Apixaban 13CD3,BMS-562247-01 13CD3
Target: Others
Fexofenadine-d6
Cat.No: T11276
Synonym: MDL-16455-d6,Terfenadine carboxylate-d6
Target: Histamine Receptor
Brexpiprazole-d8
Cat.No: T10610
Synonym: OPC-34712 D8
Target: Others
Melatonin-d4
Cat.No: T11995
Synonym: N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5
Target: Others
Brexpiprazole S-oxide D8
Cat.No: T10611
Synonym: DM-3411 D8
Target: Dopamine Receptor, 5-HT Receptor
Oleic Acid-13C
Cat.No: T35695
Synonym:
Target:
Erlotinib-13C6
Cat.No: T35915
Synonym: Erlotinib-13C6
Target:
Mycophenolic Acid-d3 Phenyl Glucuronide
Cat.No: TMIH-0359
Synonym:
Target:
Clobetasol Propionate-d5
Cat.No: T71893
Synonym:
Target:
Etoricoxib-d4
Cat.No: T11246
Synonym: MK-0663 D4,依托考昔 D4,L-791456 D4,Etoricoxib D4
Target: Others
Malathion-d10
Cat.No: TMIJ-0451
Synonym:
Target:
p-Benzoquinone-d4
Cat.No: TMIJ-0434
Synonym:
Target:
Malathion-d7
Cat.No: TMIJ-0456
Synonym:
Target:
Mavacamten-d6
Cat.No: TMID-0010
Synonym:
Target:
rac-Hesperetin-13C-d3
Cat.No: TMIJ-0108
Synonym: rac-Diosmin EP Impurity G-13C-d3
Target:
Atomoxetine-d3 hydrochloride
Cat.No: T73711
Synonym:
Target:
DM-3411-d8
Cat.No: TMIH-0198
Synonym: Brexpiprazole Metabolite
Target:
1,3,7-Trimethyluric Acid-d9
Cat.No: T71326
Synonym:
Target:
Norfluoxetine-d5 HCl
Cat.No: T71302
Synonym:
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
Guaifenesin-d3
Cat.No: T71286
Synonym:
Target:
Racecadotril-d5
Cat.No: T71145
Synonym:
Target:
Doxofylline-d4
Cat.No: TMIJ-0215
Synonym:
Target:
Doxofylline-d6
Cat.No: TMID-0118
Synonym:
Target:
Rizatriptan-d6 benzoate salt
Cat.No: T71211
Synonym:
Target:
Flufenamic Acid-d4
Cat.No: T71303
Synonym:
Target:
Elobixibat-d5
Cat.No: TMIH-0209
Synonym:
Target:
Bosentan-d4
Cat.No: T73820
Synonym:
Target:
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
Cat.No: T38356
Synonym:
Target:
Taurolithocholic Acid-d5 Sodium Salt (Major)
Cat.No: TMIJ-0332
Synonym:
Target:
Flutamide-d7
Cat.No: T69758
Synonym:
Target:
Naringenin-d4
Cat.No: TMIH-0368
Synonym:
Target:
Folpet-d4
Cat.No: TMIJ-0470
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Ambroxol-d5
Cat.No: T71143
Synonym:
Target:
Zearalenone-13C18
Cat.No: T35783
Synonym: Zearalenone-13C18
Target:
Dichlorphenamide-13C6
Cat.No: T36059
Synonym: Dichlorphenamide-13C6
Target:
Fosaprepitant-d4 Dimeglumine
Cat.No: TMIJ-0519
Synonym:
Target:
HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Nicotinamide-d4
Cat.No: T69395
Synonym:
Target:
Lornoxicam-d4
Cat.No: T71212
Synonym:
Target:
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