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The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.
The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.
产品描述 | The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain. |
靶点活性 | SAR CoV-2:190 nM (EC50) |
别名 | Z-Leu-Val-Gly-diazomethylketone |
分子量 | 445.52 |
分子式 | C22H31N5O5 |
CAS No. | 119670-30-3 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | Methanol: 50 mg/mL |
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