Citrullinated LL-37 2cit, a modified version of the LL-37 peptide, attenuates the antiviral efficacy of LL-37 against Human Rhinovirus (HRV) at a concentration of 10 μg/mL and diminishes its antibacterial properties. Furthermore, the compound diminishes RV1B-induced mRNA expression of pro-inflammatory cytokines IL-8, CCL5, and IL-6, and demonstrates a moderate decline in suppressing HRV-stimulated CCL5 secretion [1].