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AOX1 Protein, Human, Recombinant (His)

AOX1 Protein, Human, Recombinant (His)

产品编号 TMPH-00913
别名: Aldehyde oxidase, AO, Azaheterocycle hydroxylase, Aldehyde oxidase 1, AOX1

AOX1 Protein, Human, Recombinant (His) is expressed in E. coli.

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AOX1 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: AOX1 Protein, Human, Recombinant (His) (TMPH-00913)
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生物活性
技术参数
产品性质
产品描述 AOX1 Protein, Human, Recombinant (His) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-6xHis
蛋白编号 Q06278
别名 Aldehyde oxidase, AO, Azaheterocycle hydroxylase, Aldehyde oxidase 1, AOX1
氨基酸序列 FGSERMMWFSPVTLKELLEFKFKYPQAPVIMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHAYNGLTLGAGLSLAQVKDILADVVQKLPEEKTQMYHALLKHLGTLAGSQIRNMASLGGHIISRHPDSDLNPILAVGNCTLNLLSKEGKRQIPLNEQFLSKCPNADLKPQEILVSVNIPYSRK
蛋白构建 236-421 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 24.6 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

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Keywords

AOX1 Protein, Human, Recombinant (His) Aldehyde oxidase AO Azaheterocycle hydroxylase Aldehyde oxidase 1 AOX1 recombinant recombinant-proteins proteins protein

 

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